September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Optical coherence tomography based microangiography as a non-invasive imaging modality for early detection of choroido-neovascular membrane in choroidal rupture.
Author Affiliations & Notes
  • Erika Brewer
    Ophthalmology, University of Washington, Seattle, Washington, United States
  • Qinqin Zhang
    Ophthalmology, University of Washington, Seattle, Washington, United States
  • Jason P Kam
    Ophthalmology, University of Washington, Seattle, Washington, United States
  • Jin Liu
    Ophthalmology, University of Washington, Seattle, Washington, United States
  • Ruikang K Wang
    Ophthalmology, University of Washington, Seattle, Washington, United States
  • Kasra Attaran-Rezaei
    Ophthalmology, University of Washington, Seattle, Washington, United States
  • Footnotes
    Commercial Relationships   Erika Brewer, None; Qinqin Zhang, None; Jason Kam, None; Jin Liu, None; Ruikang Wang, Carl Zeiss (F), Carl Zeiss Meditec (P), Meditec (F); Kasra Attaran-Rezaei, None
  • Footnotes
    Support  Research to Prevent Blindness
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 2164. doi:
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    • Get Citation

      Erika Brewer, Qinqin Zhang, Jason P Kam, Jin Liu, Ruikang K Wang, Kasra Attaran-Rezaei; Optical coherence tomography based microangiography as a non-invasive imaging modality for early detection of choroido-neovascular membrane in choroidal rupture.. Invest. Ophthalmol. Vis. Sci. 2016;57(12):2164.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate and identify early microvascular changes in patient with choroidal rupture using optical coherence tomography (OCT) based microangiography (OMAG).

Methods : One patient (one eye) with confirmed diagnosis of choroidal rupture after sustained ocular blunt trauma underwent OMAG imaging. OMAG was performed by Zeiss spectral domain OCT-angiography prototype using a “6.5 mm x 6.5mm” field of view around macular region. The resulting images were presented into bilayers: the retinal layer and the choroidal layer.

Results : Choroidal rupture sites were easily shown on OMAG images with clear evidence of multiple breaks in Bruch’s membrane involving macula and the region superior to nerve. OMAG provided detailed vascular network patterns in the areas of choroidal rupture, showing a concern for choroidal neovascularization (CNV). The OMAG demonstrated cross sectional area to visualize CNV location relative to the other layers of the retina, identifying functional blood vessels through the lesion. The patient’s progress was followed using OMAG.

Conclusions : The images provided by OMAG give detailed microvascular findings about the macula and adjacent retinal region along with the underlying choroidal alternations. In our case, details of the architecture and vascular flow of CNVM in choroidal rupture was delivered by OMAG, which were used to follow the progression of the disease progression. Further studies are needed to assess the role of quantitative and qualitative OCT microangiography in the evaluation and treatment of choroidal rupture.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

 

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