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Pierre-Henri Becmeur, Tristan Bourcier, Arnaud Sauer; Risk Factors for Contact Lens-Related Microbial Keratitis : A Case-Control Multicenter Study. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1471.
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© ARVO (1962-2015); The Authors (2016-present)
Actually the most feared complication by ophthalmologists of contact lens (CL) wear is microbial keratitis (MK), even though its incidence remains low. It’s also a huge financial burden for the society. This study aimed to identify the risk factors of CL-related MK especially for hygiene and type of use, in a large prospective, multi center case-control study.
A multicenter case-control study was designed. The CL related MK subpopulation (Case) was compared with healthy CL wearers (Control) using a 52-item anonymous questionnaire designed to determine subject demographics, lens wear history, lens type and disinfection solution. Univariate logistic regression analyse was performed to compare both groups.
The study enrolled 497 cases and 364 controls.
The risk factors associated with the greatest increased odds of CL-related MK were as follows: extended wear, adaptation by an ophthalmologist, no follow-up, use of optician’s disinfection solution, no case replacement . The protective factors associated with the greatest reduction in OR were fitting by an ophthalmologist, female gender, hypermetropia and written and oral informations.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
Acanthamoeba Keratitis due to hygiene errors in Contact lens wear
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