September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Comparison of choroidal thickness measurements between SD-OCT and SS-OCT in normal and diseased eyes in South Asian populations.
Author Affiliations & Notes
  • Sidra Zafar
    Medical College, Aga Khan University Hospital, Karachi, Pakistan
  • Rehman Siddiqui
    Shahzad Eye Hospital, Karachi, Pakistan
    South City Hospital, Karachi, Pakistan
  • Rida Shahzad
    Medical College, Aga Khan University Hospital, Karachi, Pakistan
  • Footnotes
    Commercial Relationships   Sidra Zafar, None; Rehman Siddiqui, None; Rida Shahzad, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 2176. doi:
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    • Get Citation

      Sidra Zafar, Rehman Siddiqui, Rida Shahzad; Comparison of choroidal thickness measurements between SD-OCT and SS-OCT in normal and diseased eyes in South Asian populations.. Invest. Ophthalmol. Vis. Sci. 2016;57(12):2176.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Choroidal thickness (CT) is affected in many ocular diseases. Our study aimed to compare CT measurements between two optical coherence tomography (OCT) devices, with different laser wavelengths, in normal and diseased populations.

Methods : This was a prospective, non-interventional study comprising of 27 normal volunteers and 27 participants with retinal disease. OCT scans were performed sequentially and under standardized conditions using both spectral domain OCT (SD-OCT; Topcon 3D 2000, Topcon Inc, Tokyo, Japan) and swept source OCT (SS-OCT; Triton, Topcon Inc, Tokyo, Japan). All OCT scans were evaluated by two independent graders. Paired t tests and and intra class coefficients (ICC) were used to assess statistically significant differences between CT measurements by the two devices.

Results : Mean sub foveal CT for all 54 participants was 264.9±103.1 µm using SD-OCT (47-470 µm) and 278.5±110.5 µm with SS-OCT (range 56-502 µm), with an inter device ICC of 0.840. Greater variability was noted in the diseased eyes. The difference however was not statistically significant (p=0.132). Automatic CT measured with SS-OCT in diseased eyes was lower (183.8±99.9 µm) than manual CT measurements on either device

Conclusions : Both machines reliably measure CT. However, with SS-OCT, there is less variability in CT measurements especially when there is chorioretinal pathology.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

 

Figure 1: Bland Altman plots. (A) Comparison of SD-OCT with SS-OCT in normal eyes (B) comparison of SD-OCT with SS-OCT in diseased eyes (C) comparison of SD-OCT with SS-OCT in all participants. The horizontal axis represents the mean of SD-OCT and SS-OCT values and the vertical axis represents the difference between the values of SD-OCT and SS-OCT.

Figure 1: Bland Altman plots. (A) Comparison of SD-OCT with SS-OCT in normal eyes (B) comparison of SD-OCT with SS-OCT in diseased eyes (C) comparison of SD-OCT with SS-OCT in all participants. The horizontal axis represents the mean of SD-OCT and SS-OCT values and the vertical axis represents the difference between the values of SD-OCT and SS-OCT.

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