September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Evaluation of OCT angiography in detection of Central Serous Chorioretinopathy
Author Affiliations & Notes
  • Nikolaus Feucht
    Bldg 10, CRC, Room 3-2531, Augenklinik Rechts der Isar, Munich, Germany
  • Mathias M Maier
    Bldg 10, CRC, Room 3-2531, Augenklinik Rechts der Isar, Munich, Germany
  • C.P. Lohmann
    Bldg 10, CRC, Room 3-2531, Augenklinik Rechts der Isar, Munich, Germany
  • Lukas Reznicek
    Bldg 10, CRC, Room 3-2531, Augenklinik Rechts der Isar, Munich, Germany
  • Footnotes
    Commercial Relationships   Nikolaus Feucht, None; Mathias Maier, None; C.P. Lohmann, None; Lukas Reznicek, None
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 4958. doi:
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      Nikolaus Feucht, Mathias M Maier, C.P. Lohmann, Lukas Reznicek; Evaluation of OCT angiography in detection of Central Serous Chorioretinopathy. Invest. Ophthalmol. Vis. Sci. 2016;57(12):4958.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate the contribution of Optical Coherence Tomography angiography (OCTa) in patients with acute Central Serous Chorioretinopathy (CSC).

Methods : A consecutive series of 11 eyes of 10 healthy subjects with acute CSC were included. In all subjects, best-corrected visual acuity was obtained followed by a full clinical examination including slit lamp biomicroscopy as well as funduscopic evaluation. All patients underwent fluorescein angiography (FA), indocyanine green angiography (ICGA), optical coherence tomography (OCT) and optical coherence tomography angiography (OCTa). FA and ICGA and OCTa images were evaluated for depicting the serous detachments of the neurosensory retina and the leakage points. OCT images were evaluated by two retina specialists for depicting the serous detachments and retinal pigment epithelium (RPE) detachment as a surrogate parameter for possible leakage according to a standardized grading protocol.

Results : FA images were able to identify the leakage point in every included study eye and serous retinal detachments in 4 out of 11 eyes. ICGA images could identify the leakage point in five out of 11 eyes and serous retinal detachments in five out of 11 eyes due to a visible “demarcation line”. SD-OCT scans revealed RPE detachment in eight out of 11 study eyes and serous retinal detachment in every included eye. OCTa images through the inner, medium, outer retina or choriocapillaris could not identify leakage points in any of the included eyes. In four out of 11 eyes, it was possible to detect detached retina adjacent to the leakage point through a visible “contour line” seen in OCTa images of the outer retina. In five out of 11 eyes we observed irregular flow patterns in OCTa images through the choriocapillaris.

Conclusions : Non-invasive OCTa contributes little to diagnose acute CSC compared to current invasive (FA and ICGA) as well as non-invasive (OCT) imaging techniques. Detection of leakage points is not reproducable nevertheless we observed a irregular flow patterns in OCTa in five out of 11 eyes in the choriocapillaris layer.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

 

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