September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Reduced photoreceptor density over Choroid Nevus
Author Affiliations & Notes
  • Murilo Wendeborn Rodrigues
    Retina Division , Ribeirão Preto Medical School-University of São Paulo , Sao Jose do Rio Preto, SP, Brazil
  • Jose A Cardillo
    Retina Division , Ribeirão Preto Medical School-University of São Paulo , Sao Jose do Rio Preto, SP, Brazil
  • Emil Say
    Ocular Oncology, Wills Eye Hospital, Philadelphia, Pennsylvania, United States
  • Felipe Borges
    Retina Division , Ribeirão Preto Medical School-University of São Paulo , Sao Jose do Rio Preto, SP, Brazil
  • Rubens C Siqueira
    Retina Division , Ribeirão Preto Medical School-University of São Paulo , Sao Jose do Rio Preto, SP, Brazil
  • Rodrigo Jorge
    Retina Division , Ribeirão Preto Medical School-University of São Paulo , Sao Jose do Rio Preto, SP, Brazil
  • Footnotes
    Commercial Relationships   Murilo Rodrigues, None; Jose Cardillo, None; Emil Say, None; Felipe Borges, None; Rubens Siqueira, None; Rodrigo Jorge, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 5099. doi:
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    • Get Citation

      Murilo Wendeborn Rodrigues, Jose A Cardillo, Emil Say, Felipe Borges, Rubens C Siqueira, Rodrigo Jorge; Reduced photoreceptor density over Choroid Nevus. Invest. Ophthalmol. Vis. Sci. 2016;57(12):5099.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To assess macular photoreceptor abnormalities in eyes with posterior fundus choroid nevus lesion.

Methods : Cone density and spatial mosaic organization were assessed using adaptive optics scanning laser ophthalmoscopy (AO-SLO) images in three patients. Furthermore, color fundus, fluorescein angiography, microperimetry and Optic Coerence Tomography were performed.

Results : Cone mosaic patterns were disorganized and dark regions missing wave-guiding cones were apparent. Correlation between reduced mean retinal sensitivity obtained using microperimetry and photoreceptor decreased density obtained using AO-SLO was noted.

Conclusions : AO images provide high-resolution en face images of the structural changes in Photoreceptor (PR) mosaic at the sites overlying the lesion. Attenuation of cone PRs appears to be an important early component of structural damage in nevus and maybe correlates or predicts functional loss

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

 

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