September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Ability of novice clinicians to use the high resolution ocular coherence tomography to assess lesions of the ocular surface
Author Affiliations & Notes
  • Michael Yim
    Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida, United States
  • Anat Galor
    Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida, United States
    Ophthalmology, Department of Veterans Affairs, Miami, Florida, United States
  • Afshan Nanji
    Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida, United States
  • Madhura Joag
    Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida, United States
  • William J Feuer
    Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida, United States
  • Carol Karp
    Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida, United States
  • Footnotes
    Commercial Relationships   Michael Yim, None; Anat Galor, Jimmy and Gaye Bryan Grant (F), NIH Center Core Grant P30EY014801 (F), Research to Prevent Blindness Unrestricted Grant (F), Ronald and Alicia Lepke Grant (F), Supported by the Department of Veterans Affairs, Veterans Health Administration, Office of Research and Development, Clinical Sciences Research and Development’s Career Development Award (F), The Gordon Charitable Trust (F), The Lee and Claire Hager Grant (F); Afshan Nanji, None; Madhura Joag, None; William Feuer, None; Carol Karp, Richard Azar Family Grant (F)
  • Footnotes
    Support  Supported by the Department of Veterans Affairs, Veterans Health Administration, Office of Research and Development, Clinical Sciences Research and Development’s Career Development Award CDA-2-024-10S (Dr. Galor), NIH Center Core Grant P30EY014801, Research to Prevent Blindness Unrestricted Grant, the Ronald and Alicia Lepke Grant, The Lee and Claire Hager Grant, the Jimmy and Gaye Bryan Grant, The Gordon Charitable Trust, and the Richard Azar Family Grant
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 5717. doi:
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      Michael Yim, Anat Galor, Afshan Nanji, Madhura Joag, William J Feuer, Carol Karp; Ability of novice clinicians to use the high resolution ocular coherence tomography to assess lesions of the ocular surface. Invest. Ophthalmol. Vis. Sci. 2016;57(12):5717.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To assess the ability of novice clinicians to use the high resolution anterior segment ocular coherence tomography (HR-OCT) to diagnose various lesions of the ocular surface and cornea

Methods : 26 black and white HR-OCT images were projected and clinicians were asked to determine whether the lesions represented ocular surface squamous neoplasia (OSSN) or another ocular surface pathology. A 20-minute instructional lecture was then given on how to read HR-OCT images and the same 26 images were shown. The clinicians were then asked to repeat their assessment of the lesions.

Results : The mean frequency of correct identification of the 26 lesions was 70% (standard deviation 15%) prior to instruction and after a short lecture, the frequency of correct identification improved to 84% (SD 9%), p=0.002. On average, novice clinicians were more accurate in correctly determining that a lesion was not an OSSN over determining that a lesion was an OSSN (p=0.001). Some lesions (both OSSN and not OSSN), however, were more difficult to interpret than others.

Conclusions : This study demonstrates that HR-OCT can aid novice clinicians in identifying lesions as being or not being an OSSN.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

 

A classic image of an OSSN on HR HR-OCT. All features of OSSN (epithelial thickening, hyperreflectivity, and abrupt transition (arrow) from normal to abnormal epithelium) are seen.

A classic image of an OSSN on HR HR-OCT. All features of OSSN (epithelial thickening, hyperreflectivity, and abrupt transition (arrow) from normal to abnormal epithelium) are seen.

 

A more subtle image of OSSN on HR HR-OCT. Note only subtle epithelial thickening. The lesion is highly hyper-reflective and an abrupt transition is seen on the conjunctival side (arrow), but less defined on the corneal side.

A more subtle image of OSSN on HR HR-OCT. Note only subtle epithelial thickening. The lesion is highly hyper-reflective and an abrupt transition is seen on the conjunctival side (arrow), but less defined on the corneal side.

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