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Mayer Srour, Giuseppe Querques, Oudy Semoun, Ala Elameen, Alexandra Miere, Anne Sikorav, Olivia Zambrowski, Eric H Souied; Optical coherence tomography angiography characteristics of polypoidal choroidal vasculopathy. Invest. Ophthalmol. Vis. Sci. 2016;57(12):27.
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© ARVO (1962-2015); The Authors (2016-present)
To analyze the morphological characteristics of polypoidal choroidal vasculopathy (PCV) on optical coherence tomography angiography (OCT-A).
Prospective study with consecutive patients affected with PCV were included. All patients underwent a complete ophthalmological examination including fundus photography, fluorescein angiography (FA), indocyanine green angiography (ICGA), spectral-domain (SD)-OCT and OCT-A.
Twelve eyes of 12 patients (mean age 72.6±10.5 years; 4 men and 8 women) were included for analysis. In all eyes (12/12) the segmentation of the choriocapillaris layer on OCT-A revealed the branching vascular network (BVN) as a hyper-flow lesion. OCT-A segmentation of the choriocapillaris layer in correspondence of the polypoidal lesion showed in 3/12 eyes (25%) a hyper-flow round structure, surrounded by a hypo-intense halo, and in 9/12 eyes (75%) a hypo-flow round structure.
The OCT-A is a non-invasive imaging modality allowing the visualization of different structures in PCV. The BVN is constantlyclearly detected. The hypo-flow round structure appearance of the polyp in OCT-A, is probably due to an unusual blood flow inside the polypoidal lesions, contrasting with the branching vascular network. Further improvement in OCT-A knowledge will provide information on the specificity of the different intensity characteristics in PCV.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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