September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Correlation of optic nerve OCT on Zeiss Cirrus HD and Humphrey visual field defects at WJB Dorn VA; does signal strength matter?
Author Affiliations & Notes
  • Kelton Wigington
    Ophthalmology, Palmetto Health University of South Carolina, Lexington, South Carolina, United States
  • Riley Stroman
    University of South Carolina School of Medicine, Columbia, South Carolina, United States
  • Daniela Whiteside
    Ophthalmology, Palmetto Health University of South Carolina, Lexington, South Carolina, United States
  • Footnotes
    Commercial Relationships   Kelton Wigington, None; Riley Stroman, None; Daniela Whiteside, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 378. doi:
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      Kelton Wigington, Riley Stroman, Daniela Whiteside; Correlation of optic nerve OCT on Zeiss Cirrus HD and Humphrey visual field defects at WJB Dorn VA; does signal strength matter?. Invest. Ophthalmol. Vis. Sci. 2016;57(12):378.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : We performed a retrospective chart review to test the hypothesis that the signal strength of our Zeiss Cirrus HD-OCT model 400 glaucoma OCT affects the validity of the test results. We also sought to discover what on the Zeiss printout is the best correlation to visual field deficit on the Humphrey visual field (HVF).

Methods : We found 55 eyes of glaucoma suspect and glaucoma patient with a reliable Humphrey 24-2 visual field (HVF) and a Zeiss glaucoma OCT performed between 4/2015 and 11/2015 at WJB Dorn VA Hospital in Columbia, SC. Excluded patients with angle closure glaucoma and secondary open angle glaucoma. The retinal nerve fiber layer (RNFL) quadrant and clock hour thicknesses were compared to the visual field deficits to determine if the area of thinning corresponded to the area of field loss. Pearson correlation coefficients were calculated using Microsoft Excel between data.

Results : -49.09% of eyes positive correlation between RNFL quadrant thinning and HVF deficits
-61.8% of eyes positive correlation between RNFL clock hour thinning and HVF deficits
-signal strength did not show linear correlation to whether the glaucoma OCT RNFL thinning corresponded to the HVF deficits
-Rim area showed strong positive linear correlation to MD and strong negative linear correlation to PSD on HVF
-Ratio of rim area to disc area showed moderate positive linear correlation to MD but not to PSD
- cup to disc ratio, cup volume, and cup volume to disc area ratio did not show strong correlations to MD or PSD

Conclusions :
1. At the WJB Dorn VA hospital, signal strength variability did not affect whether the RNFL thinning (quadrants or clock hours) shown on the OCT report from the Zeiss Cirrus HD OCT correlated to the visual field deficits on the HVF
2. Iis best to use the RNFL clock hour thinning section reported on the print out rather than the RNFL quadrant thinning section as the clock hours correlated better to the area of visual field deficit on HVF. Also, the rim area, and the calculated rim:disc area ratio had strong correlations to the MD and PSD numbers on the HVF print out. Further studies would need to be done at our institution to see if following the rim:disc area ratio and the rim area would also correspond well to the progression of MD and PSD.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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