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Livia Teo, Chang Yeom Kim, Dong Kyu Kim, Jin Sook Yoon; SURGICAL OUTCOMES OF PORCINE ACELLULAR DERMIS GRAFT IN SOCKET AND EYELID RECONSTRUCTION: A COMPARISON WITH ORAL MUCOSAL GRAFT. Invest. Ophthalmol. Vis. Sci. 2016;57(12):684. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To compare the efficacy of the Permacol™ graft with autologous buccal mucosal graft in socket and eyelid reconstruction, with emphasis on the postoperative vascularization and fibrosis of each graft.
This was a retrospective comparative study. Ten patients underwent Permacol™ graft reconstruction and 44 patients underwent buccal mucosal graft reconstruction. The time necessary for the graft surface to be completely vascularized and the fornix depth of the conjunctival sac in anophthalmic patients was measured.
All ten patients in the Permacol group had unilateral contracted anophthalmic sockets. Seven eyelids (70%) in the anophthalmic socket group had a good outcome with improvement in lower eyelid position and prosthesis retention. Nine out of ten eyelids (90%) in this group showed complete vascularization of the graft with minimal fibrosis at 2.6± 1.9 months postoperatively, while the grafted buccal mucosa was fully vascularized at 1.1± 0.3 months postoperatively (P< 0.01). Postoperative fornix depth in the Permacol™ group was 9.1 ± 2.2 mm compared to14.9 ± 4.5 mm in the buccal mucosal graft group (P< 0.01).
The Permacol™ graft can be a useful spacer graft material in anophthalmic socket and eyelid patients. It takes longer to vascularize and undergoes greater graft shrinkage with time when compared to buccal mucosal graft.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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