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Young Jun Woo, Do Wook Kim, Ji Won Kim, Jin Sook Yoon; Clinical Features of Graves Orbitopathy Patients with Recurred Orbital Inflammation after Decompression. Invest. Ophthalmol. Vis. Sci. 2016;57(12):701.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate clinical features of Graves orbitopathy (GO) patients with recurred orbital inflammation after decompression.
Ninety-seven patients who underwent orbital decompression because of disfiguring proptosis (n = 60) or orbital congestion including compressive optic neuropathy (ON) (n = 37) were evaluated. Demographics, ophthalmic manifestations, and biochemical parameters were reviewed. Preoperative factors affecting occurrence of orbital inflammation after decompression were investigated with logistic regression analyses.
Seventeen patients experienced recurred inflammation of GO after orbital decompression. All had undergone surgery because of orbital congestion or ON. Univariate logistic regression analysis identified current smoking (P = 0.042), modified NOSPECS score (P = 0.013), and presence of ON (P = 0.019) as significant factors for recurred inflammation of GO. Multivariate logistic regression analysis revealed that current smoking (P = 0.022) and presence of ON (P = 0.011) were associated with postoperative recurred inflammation of GO.
Orbital inflammation after decompression tends to occur in GO patients with preoperative orbital congestion or ON. The presence of ON and smoking status at the time of surgery were significant positive, independent factors for recurred inflammation of GO in group of orbital congestion or ON. Patients with these factors should be carefully observed for recurrence of orbital inflammation even if GO became inactive after orbital decompression.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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