September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Long-term surgical outcomes of retinal detachment in patients with Stickler syndrome
Author Affiliations & Notes
  • Devasis Reddy
    Oakland University William Beaumont School of Medicine, Royal Oak, Michigan, United States
  • Yoshihiro Yonekawa
    Oakland University William Beaumont School of Medicine, Royal Oak, Michigan, United States
    Associated Retinal Consultants, Royal Oak, Michigan, United States
  • Benjamin J Thomas
    Oakland University William Beaumont School of Medicine, Royal Oak, Michigan, United States
    Associated Retinal Consultants, Royal Oak, Michigan, United States
  • Eric Nudleman
    Shiley Eye Institute, La Jolla, California, United States
  • George A. Williams
    Oakland University William Beaumont School of Medicine, Royal Oak, Michigan, United States
    Associated Retinal Consultants, Royal Oak, Michigan, United States
  • Footnotes
    Commercial Relationships   Devasis Reddy, None; Yoshihiro Yonekawa, None; Benjamin Thomas, None; Eric Nudleman, None; George Williams, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 1051. doi:
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    • Get Citation

      Devasis Reddy, Yoshihiro Yonekawa, Benjamin J Thomas, Eric Nudleman, George A. Williams; Long-term surgical outcomes of retinal detachment in patients with Stickler syndrome. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1051.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To present the long-term anatomic and visual outcomes of retinal detachment repair in patients with Stickler syndrome.

Methods : We conducted a retrospective, single-center, interventional, consecutive case series of patients with Stickler syndrome who underwent retinal reattachment surgery at our institution and seen between 2009 and 2014.

Results : Sixteen eyes from 13 patients (mean age 10.5 years) were identified. Patients underwent on average 3.1 surgeries (range 1-13), and had 94 months (range 5-313) of post-operative follow-up. Twelve (75%) eyes developed proliferative vitreoretinopathy. All eyes eventually had successful reattachment with 10 eyes (63%) requiring silicone oil at last follow-up. Mean visual acuity before surgery was 20/914 (1.66 LogMar), and 20/796 (1.60 LogMar) at final follow-up (P = 0.81). There was a correlation between presenting and final visual acuity (P < 0.001). Patients with worse presenting visual acuities were more likely to require silicone oil tamponade at last examination (P = 0.04). In 6 of 13 patients (46%) there was bilateral retinal pathology seen during the study period. 4 of these patients developed bilateral retinal detachment, and 2 of these patients developed retinal tears in the fellow eyes. Seven fellow eyes were treated with prophylactic 360 degree laser photocoagulation. The average duration of time between retinal detachment in the presenting eye and tears or detachments in the fellow eye was 2 months (range 0-10).

Conclusions : Retinal detachment repair in patients with Stickler syndrome usually requires multiple surgeries to achieve reattachment. In our series, all retinal detachments were successfully reattached, but visual outcomes were variable, and correlated with presenting visual acuity.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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