September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
With or without internal limiting membrane peeling during vitrectomy for epiretinal membrane: A systematic review of literature and meta-analysis
Author Affiliations & Notes
  • Kunihiro Azuma
    Eguchi Eye Hospital, Hakodate, Japan
    Department of Ophthalomology, University of Tokyo, Hakodate, Hokkaido, Japan
  • Shuichiro Eguchi
    Eguchi Eye Hospital, Hakodate, Japan
  • Takashi Ueta
    Department of Ophthalomology, University of Tokyo, Hakodate, Hokkaido, Japan
  • Footnotes
    Commercial Relationships   Kunihiro Azuma, None; Shuichiro Eguchi, None; Takashi Ueta, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 1057. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to Subscribers Only
      Sign In or Create an Account ×
    • Get Citation

      Kunihiro Azuma, Shuichiro Eguchi, Takashi Ueta; With or without internal limiting membrane peeling during vitrectomy for epiretinal membrane: A systematic review of literature and meta-analysis. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1057.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : Additional internal limiting membrane (ILM) peeling in vitrectomy for epiretinal membrane (ERM) is a widely accepted surgical procedure, but its beneficial effects have still been controversial. Thus, we conducted a systematic review of literature and meta-analysis to summarize the current evidence on the effects of ILM peeling in vitrectomy for ERM.

Methods : Medline, CENTRAL, and Embase were systematically reviewed. The terms used for the systematic search were “epiretinal membrane,” “fibrovascular membrane,” “pucker,” “internal limiting membrane,” and “inner limiting membrane.” Eligible studies included randomized or nonrandomized studies that compared surgical outcomes of vitrectomy with or without ILM peeling for idiopathic ERM. Outcome measures were best-corrected visual acuity (BCVA), central macular thickness (CMT), and ERM recurrence. The longest postoperative data were used to analysis.

Results : Twelve studies that included 2029 eyes were selected. Among 12 studies, two studies were prospective studies, and the others were retrospective comparative studies. There are no randomized controlled studies in this current meta-analysis. The duration of follow-up was from 6 to 18 months. There was no significant difference in preoperative BCVA (mean difference (MD) 0.02 logMAR; 95%CI −0.03 to 0.06) and CMT (MD 6.63µm; 95%CI −15.89 to 29.15; P = 0.82). There was no significant difference in postoperative BCVA (MD 0.01 logMAR; 95%CI −0.05 to 0.08) and CMT (MD 13.38; 95%CI −13.55 to 40.31). The ERM recurrence rate was significantly lower with ILM peeling than without ILM peeling (Odds ratio 0.26; 95%CI 0.12 to 0.54).

Conclusions : Additional ILM peeling in vitrectomy for idiopathic ERM could contribute to the lower recurrence rate of ERM, while it does not significantly influence BCVA and CMT.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×