September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Correlation of postoperative vision and fundus autofluorescence after vitrectomy for epiretinal membrane
Author Affiliations & Notes
  • Ryo Tokizawa
    Ophthalmology, Kyorin Eye Center, Mitaka, Tokyo, Japan
  • Makoto Inoue
    Ophthalmology, Kyorin Eye Center, Mitaka, Tokyo, Japan
  • Yoshiyuki Kita
    Ophthalmology, Kyorin Eye Center, Mitaka, Tokyo, Japan
  • Yuji Itoh
    Ophthalmology, Kyorin Eye Center, Mitaka, Tokyo, Japan
  • Takashi Koto
    Ophthalmology, Kyorin Eye Center, Mitaka, Tokyo, Japan
  • Akito Hirakata
    Ophthalmology, Kyorin Eye Center, Mitaka, Tokyo, Japan
  • Footnotes
    Commercial Relationships   Ryo Tokizawa, None; Makoto Inoue, None; Yoshiyuki Kita, None; Yuji Itoh, None; Takashi Koto, None; Akito Hirakata, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 1091. doi:
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    • Get Citation

      Ryo Tokizawa, Makoto Inoue, Yoshiyuki Kita, Yuji Itoh, Takashi Koto, Akito Hirakata; Correlation of postoperative vision and fundus autofluorescence after vitrectomy for epiretinal membrane. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1091.

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      © 2017 Association for Research in Vision and Ophthalmology.

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Abstract

Purpose : Fundus autofluorescence (FAF) at the macula originates from hyperfluorescence from retinal pigment epithelium (RPE) and blockage of hyperfluorescence by macular pigment; xythantophyll. We evaluate whether presence of FAF may correlate to the postoperative visual outcome for epiretinal membrane.

Methods : Ninety-one eyes with epiretinal membrane were performed vitreous surgery, epiretinal membrane removal and internal limiting membrane (ILM) peeling. Presence of hyperfluorescence in FAF at the macular area and best-corrected visual acuity (BCVA) was evaluated preoperatively and at postoperative 1, 3, and 6 months with Optos ultra-wide angle imaging.

Results : Postoperative hyperfluorescence was detected in 23 of 89 eyes (26%) at 1 month, 19 of 84 eyes (23%) at 3 months, 10 of 53 eyes (19%) at 6 months. Postoperative BCVA was worse in eyes with hyperfluorescence at the macula at 1 month (P<0.0001), 3 months (P<0.0001), 6 months (P=0.0004) comparing to the eyes without hyperfluorescence.

Conclusions : Postoperative visual recovery after epiretinal membrane surgery may correlate with the presence of persistent hyperfluorescence at the macula which originates from retinal and RPE damage and volume of macular pigment.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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