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William Flanary, Jesse Vislisel, Michael D Wagoner, Matthew Raecker, Benjamin Thomas Aldrich, M. Bridget zimmerman, Kenneth M Goins, Mark A Greiner; Cystoid Macular Edema after DMEK and Recent Versus Remote Cataract Surgery. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1193.
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© ARVO (1962-2015); The Authors (2016-present)
The purpose of this study was to compare the incidence of visually significant cystoid macular edema (VS-CME) in pseudophakic eyes following Descemet membrane endothelial keratoplasty (DMEK) performed after recent versus remote cataract surgery.
A retrospective chart review was performed of 173 consecutive eyes that underwent DMEK without concurrent cataract surgery at the University of Iowa between October 2012 and December 2014. DMEK procedures were classified as staged if performed <6 months after cataract surgery and solitary if performed ≥6 months after cataract surgery. Possible confounders, including a history of diabetes in the recipient, were tracked. Macular optical coherence tomography was performed to detect VS-CME 1 month after DMEK if the best-corrected visual acuity was ≤20/30 in a clear cornea with no other reason for visual compromise.
Staged DMEK was performed in 88 eyes (50.9%) and solitary DMEK in 85 eyes (49.1%). The incidence of VS-CME was 8.0% (7 of 88 eyes) in the staged DMEK group and 7.0% (6 of 85 eyes) in the solitary DMEK group (P=0.823) The incidence of VS-CME did not differ significantly between staged and solitary DMEK groups regardless of recipient diabetic status. All cases of VS-CME resolved within 6 months on topical therapy.
The incidence of postoperative VS-CME after DMEK is similar for recently or remotely performed cataract surgery.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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