September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Comparison of lamellar keratoplasty versus penetrating keratoplasty for macular corneal dystrophy
Author Affiliations & Notes
  • Ahmad M Alaraj
    anterior segment, king khaled eye specialist hospital, Riyadh, Saudi Arabia
    Anterior segment, Qassim University, Buridah, Saudi Arabia
  • Samar A Al-Swailem
    anterior segment, king khaled eye specialist hospital, Riyadh, Saudi Arabia
  • Footnotes
    Commercial Relationships   Ahmad Alaraj, None; Samar Al-Swailem, None
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 1238. doi:
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    • Get Citation

      Ahmad M Alaraj, Samar A Al-Swailem; Comparison of lamellar keratoplasty versus penetrating keratoplasty for macular corneal dystrophy. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1238.

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      © 2017 Association for Research in Vision and Ophthalmology.

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Abstract

Purpose : To compare postoperative outcomes of anterior lamellar keratoplasty (ALK), big-bubble deep anterior Lamellar keratoplasty (DALK) and penetrating keratoplasty (PKP) for macular corneal dystrophy (MCD).

Methods : Retrospective analysis of 10 ALK eyes, 24 DALK eyes and 140 PKP eyes in 98 patients with MCD.

Results : Median follow-up was 3.62 (range 1.04-16.02) years and 5.89 (range 1.0-17.0) years in the lamellar keratoplasties and PKP groups, respectively. Median best-corrected visual acuity (BCVA) was 20/80 and 20/40 in ALK and DALK groups, respectively (P=0.006). Median BCVA was 20/40 in PKP group. The likely hood of achieving 20/40 or better was higher in PKP vs. DALK groups, but was not statistically significant. Graft survived in 30% (3 eyes) and 100% (24 eyes) in ALK and DALK groups, respectively (P=0.0001). Graft survived in 95% (133 eyes) in PKP group. Recurrence (71.4%) was the main cause of graft failure in ALK group, while recurrence (42.8%) and irreversible rejection (57.1%) were the main causes of graft failure in PKP group.

Conclusions : ALK for MCD is associated with poor prognosis for graft survival and visual result. In comparison to PKP, DALK has a higher probability of graft survival, a lower complication rate, and a comparable visual result.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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