September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Retinal ganglion cell structure and electrophysiology during injury and recovery
Author Affiliations & Notes
  • Jonathan G Crowston
    Ctr for Eye Research Australia, East Melbourne, Victoria, Australia
    Ophthalmology, University of Melbourne, Melbourne, Victoria, Australia
  • Footnotes
    Commercial Relationships   Jonathan Crowston, None
  • Footnotes
    Support  NHMRC
Investigative Ophthalmology & Visual Science September 2016, Vol.57, No Pagination Specified. doi:
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      Jonathan G Crowston; Retinal ganglion cell structure and electrophysiology during injury and recovery. Invest. Ophthalmol. Vis. Sci. 201657(12):.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Presentation Description : This presentation will detail function and structural changes in retinal ganglion cells in response to a sub-ischemic acute IOP injury that leads to low levels of RGC loss. We report RGC functional responses using full field ERG and single-cell patch clamping. We will also report on RGC structural changes up to 28 days following injury. These data show that RGCs can recover function after a prolonged period of functional loss and that structure and function correlate poorly during the recovery period.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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