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Paulina Tolosa Tort, Roberto Gonzalez-Salinas, Carlota García-Gutiérrez, Vidal Soberon, Gerardo Garcia-Aguirre, Virgilio Morales-Canton, Raul Velez-Montoya, Juan C Soliz-Sáinz, Pablo García-Solis, Manuel Sáenz-de-Viteri, Vinicio García-Solis; Description of ocular comorbidities associated to a surgical cohort of proliferative diabetic retinopathy patients in Mexico. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1602.
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© ARVO (1962-2015); The Authors (2016-present)
One of the most common complications of diabetes is retinopathy, currently considered the first cause of irreversible blindness in working age adults in developing countries. Associations between systemic factors and progression of retinopathy are well known. This study aims to describe the ocular comorbidities associated to DR in Mexico, and to outline the determinants of retinopathy severity in DR-operated patients in a Mexican cohort.
This is a cross-sectional, retrospective study including 282 patients diagnosed with diabetic retinopathy (DR) that underwent vitreo-retinal surgery from May 2013 to June 2014. The prevalence of ocular comorbidities and major factors for visual impairment were estimated at the Retina Department of the Association to Prevent Blindness in Mexico.
The observed overall prevalence for PDR was 25.43%. The mild visual impairment (VI) prevalence for the PDR group was 17.14%, whereas in the NPDR group it was 25.17% (P=0.033; OR [95% CI]=0.5; 0.24-1.05). Significant differences were also found for prevalence of grade 1 cataracts in relation to diabetic retinopathy (DR) (4.28% in PDR vs 8.71% in NPDR respectively; P=0.02; OR [95% CI]=0.4; 0.19-0.84). The no light perception category showed significant differences between DR groups (6.42% in the PDR vs 1.06% in the NPDR; P=0.0001; OR [95% CI]=11.05; 3-39.5). There were no statistically significant differences between groups in terms of age, gender, duration of diabetes, age at T2DM diagnosis, serum glucose and HbA1c levels.
The presence of PDR revealed an association with VI, and significant differences were found between groups, in both, the VA and the BCVA measurements. The major comorbidities found, neovascular glaucoma and STDR, were significantly associated with VI in relation to the type of DR.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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