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Eleonora Corbelli, Maria Vittoria Cicinelli, Adriano Carnevali, Andrea Mazzaferro, Maurizio Battaglia Parodi, Lea Querques, Ilaria Zucchiatti, Lucia Benatti, Francesco Bandello, Giuseppe Querques; OCT-ANGIOGRAPHY OF ANGIOID STREAKS. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1640.
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Standard multimodal imaging is known to be crucial for the management and follow-up of angioid streaks (AS). Optical coherence tomography angiography (OCT-A) is a new imaging technique that allows a better visualization of blood flow in the retina and in the choroid capillary network. This study analyzes the features of the AS on OCT-A.
We retrospectively analyzed 15 eyes of 9 subjects (6 males and 3 females, age 57±13) affected by AS, with and without choroidal neovascularization (CNV). All patients underwent standard multimodal imaging, including multicolor imaging, infrared retinography (IR), blue autofluorescence (BAF), fluorescence angiography (FA), spectral-domain (SD)-OCT and OCT-A (Angioplex™, CIRRUS HD-OCT models 5000, Carl Zeiss Meditec, Inc., Dublin, USA). We studied the features of AS on OCT-A and compared them with the findings of angiography and SD-OCT.
The OCT-A revealed a total of 40 angioid streaks. Most of them (35 AS) appeared as a choriocapillary rarefaction, corresponding to an hypo-reflective area of the RPE-Bruch’s membrane complex on SD-OCT. Five AS were not clearly evident on OCT-A choriocapillary segmentation. Choroidal segmentation was found to be normal in all patients in correspondence if AS.
OCT-A is a promising and non-invasive imaging technology for the diagnosis and follow-up of AS. On OCT-A in most cases a rarefaction of the choriocapillary network is evident in correspondence of AS.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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