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Jordan Burnham, Brian Tieu, Matt Olsen, Jeffrey St.John, Ching Jygh Chen; Optical Coherence Tomography Angiographic Evaluation of Patients with Acute Multifocal Placoid Pigment Epitheliopathy. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1641.
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© ARVO (1962-2015); The Authors (2016-present)
Split Spectrum Amplitude Decorrelation Angiography (SSADA) based Optical Coherence Tomography Angiography (OCTA) evaluation of Acute Multifocal Placoid Pigment Epitheliopathy (AMPPE).
Retrospective review of SSADA based OCTA, SD-OCT and FA on patients with AMPPE, and to observe the choroidal vascular changes over the clinical course of this disease.
2 patients with AMPPE were evaluated using OCTA. During the acute phase, OCTA detected no blood flow in the choriocapillaris corresponding to retinal placoid lesions on clinical exam, but there was surrounding increased flow. In addition, there were some hyporeflective areas in the RPE and outer retina corresponding to the retinal placoid lesions. There was no significant vascular flow changes in the superficial and deep retina. In the resolution stage of this disease, blood flow resumed and a pigment shadowing effect was noted.
OCTA showed a significant deprivation of choriocapillaris blood flow in the center of each placoid lesion. Increased flow was detected at the border. This could be due to a vasculitis involving the choriocapillaris with vascular occlusion in the center of each involved choriocapillary lobule and dilation of surrounding inflamed choriocapillaris.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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