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Andrea Mazzaferro, Eleonora Corbelli, Maria Vittoria Cicinelli, Adriano Carnevali, Maurizio Battaglia Parodi, Ilaria Zucchiatti, Lucia Benatti, Lea Querques, Francesco Bandello, Giuseppe Querques; OCT-ANGIOGRAPHY FEATURES OF CHOROIDAL NEOVASCULARIZATION SECONDARY TO ANGIOID STREAKS. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1647.
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© 2017 Association for Research in Vision and Ophthalmology.
Choroidal neovascularization (CNV) is one of the main complications of an angioid streaks (AS). Aim of the study is to describe the Optical Coherence Tomography Angiography (OCT-A) features of CNV secondary to AS.
We retrospectively analyzed 9 patients presenting between September 2015 and November 2015 at the Medical Retina Service of the University Vita-Salute San Raffaele in Milan . Each patient underwent multimodal retinal imaging: multicolor imaging, fluorescein angiography (FA), spectral-domain (SD)-OCT, OCT-A (AngioPlex™, CIRRUS HD-OCT models 5000, Carl Zeiss Meditec, Inc., Dublin, USA). OCT-A features of CNV were analyzed and two types of denomination were proposed: “interlacing” and “tangled” vascular network. Automatic segmentation provided by the machine software was manually adjusted.
Thirteen eyes of 9 patients (5 males / 4 females) with AS and CNV (mean age 60.8 ± 8.2 years) were included for analysis. In all eyes we found agreement between OCTA, FA and SD-OCT images in detecting CNV. CNV appeared on OCT-A as a hyper-intense vascular network of variable size. Seven eyes (53.8 %) showed an “interlacing” network and 6 eyes (46.2 %) a “tangled” network. The interlacing appearance was more often associated with signs of activity on multimodal imaging.
OCT-A is a very useful non-invasive tool to detect and characterize CNV associated with AS.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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