September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Retinal Oximetry in a Healthy Japanese Population
Author Affiliations & Notes
  • Yuki Nakano
    Department of Ophthalmology, Kagawa University Faculty of Medicine, Kida-gun, Kagawa, Japan
  • Takeru Shimazaki
    Department of Ophthalmology, Kagawa University Faculty of Medicine, Kida-gun, Kagawa, Japan
  • Nobuko Kobayashi
    Department of Ophthalmology, Kagawa University Faculty of Medicine, Kida-gun, Kagawa, Japan
  • Yukiko Miyoshi
    Department of Ophthalmology, Kagawa University Faculty of Medicine, Kida-gun, Kagawa, Japan
  • Aoi Ono
    Department of Ophthalmology, Kagawa University Faculty of Medicine, Kida-gun, Kagawa, Japan
  • Mamoru Kobayashi
    Department of Ophthalmology, Kagawa University Faculty of Medicine, Kida-gun, Kagawa, Japan
  • Chieko Shiragami
    Department of Ophthalmology, Kagawa University Faculty of Medicine, Kida-gun, Kagawa, Japan
  • Kazuyuki Hirooka
    Department of Ophthalmology, Kagawa University Faculty of Medicine, Kida-gun, Kagawa, Japan
  • Akitaka Tsujikawa
    Department of Ophthalmology, Kagawa University Faculty of Medicine, Kida-gun, Kagawa, Japan
  • Footnotes
    Commercial Relationships   Yuki Nakano, None; Takeru Shimazaki, None; Nobuko Kobayashi, None; Yukiko Miyoshi, None; Aoi Ono, None; Mamoru Kobayashi, None; Chieko Shiragami, None; Kazuyuki Hirooka, None; Akitaka Tsujikawa, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 1664. doi:
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    • Get Citation

      Yuki Nakano, Takeru Shimazaki, Nobuko Kobayashi, Yukiko Miyoshi, Aoi Ono, Mamoru Kobayashi, Chieko Shiragami, Kazuyuki Hirooka, Akitaka Tsujikawa; Retinal Oximetry in a Healthy Japanese Population. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1664.

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      © 2017 Association for Research in Vision and Ophthalmology.

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Abstract

Purpose : To establish the normative database of retinal oximetry using Oxymap T1 in a healthy Japanese population, and study the reproducibility and validity of the measurements in Japanese.

Methods : We measured oxygen saturation in the major retinal vessels with Oxymap T1 in 252 eyes of 252 healthy Japanese subjects. Reproducibility of retinal oximetry was investigated using 20 eyes of 20 healthy subjects. To investigate the validity of the measurements, retinal oximetry was performed before and after breathing through a paper bag in 12 eyes of 12 healthy subjects.

Results : The mean retinal oxygen saturation of 4 quadrants in healthy Japanese was 97.0 ± 6.9% in arteries and 52.8 ± 8.3% in veins. The mean arteriovenous difference in oxygen saturation was 44.2 ± 9.2%. Interphotograph, intervisit, and interevaluator intraclass correlation coefficients were 0.936–0.979, 0.809–0.837, and 0.732–0.947, respectively. In the major retinal arteries, oxygen saturation increased with age (r=0.18, p<0.01), at a rate of 0.67% per 10 years. However, venous oxygen saturation showed no correlation with age. In parallel with systemic oxygen saturation, arterial oxygen saturation decreased from 97.2 ± 5.4% to 90.2 ± 6.7% after paper-bag breathing (p<0.01), and returned to the baseline level (97.0 ± 5.9%) after room-air breathing. However, venous oxygen saturation showed no significant change with paper-bag breathing.

Conclusions : Mean retinal oximetry in 4 quadrants with Oxymap T1 has high reproducibility and validity.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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