Purchase this article with an account.
Aravind Haripriya, Chandrasekaran Shivakumar, Madhu Shekhar, Rengaraj Venkatesh, Kalpana Narendran, Alan L Robin; Aravind Pseudoexfoliation (XFS) Study (APEX): 3 year post operative results. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1987.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
There are questions regarding both the intraoperative and long-term post-operative complications in eyes with pseudoexfoliation (XFS). Our study aims to evaluate the long term complications in XFS eyes who underwent phacoemulsification without prior clinical lens subluxation.
We prospectively randomized 1000 eyes with clinically graded XFS with or without glaucoma without preexisting phacodonesis into 4 groups: 3-piece Acrysof lenses (MA60AC) and single piece Acrysof lenses (SA60AT) with and without CTRs. We compared these to 500 eyes with cataracts alone randomized to receive either a SA60AT or MA60AC without CTR. All surgical and late postoperative complications were noted and analysed for each of 2 groups. Eyes were followed intraoperatively, at 1 day, 1, 3 and 6 months, 1, 2 and 3 years and will be followed up yearly for 10 years.
We report the 3 year postoperative results of 857 XFS eyes and 447 controls. Mean IOP was 13.22(3.01) XFS & 13.27(2.93) Control, (p=0.783). There were no significant differences in IOL decentration (0.7 % vs. 0.67%, p=0.999), central posterior capsular opacification (4.5% vs. 6%, p=0.244), or new onset of glaucoma (1.1 % vs 2.1 %, p=0.081) between the two groups. There was no significant intergroup difference as well in the above variables. The three year, corrected distance VA > 6/9 was 98.02 % XFS compared to 98.2 % controls (p= 0.808). The overall mortality rate was 5.4 % (6 % vs 4%, p=0.161 ) with highest cardiac arrest / CVA accounting for 1.2 % (1.5 % vs 0.6%, p=0.299).
In eyes with mild XFS, there was no increased risk of complications at 3 years postoperative irrespective of IOL type or use of CTR. However longer follow-up will reveal if lens choice or the use of a CTR is related to significantly higher rate of late post op complications.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
This PDF is available to Subscribers Only