September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Analysis of age-related Choroidal Layers thinning in Healthy Eyes Using Swept-Source Optical Coherence Tomography.
Author Affiliations & Notes
  • Jorge Ruiz-Medrano
    Ophthalmology, Hospital Universitario Clínico San Carlos, Madrid, Spain
  • Marcos Javier Rubio Caso
    Hospital Bellvitge, Barcelona, Spain
  • Ignacio Flores-Moreno
    Ophthalmology, Hospital Universitario Clínico San Carlos, Madrid, Spain
  • Pablo Peña-Garcia
    Universidad de Castilla-La Mancha, Albacete, Spain
  • Javier Montero
    Pio del Rio Hortega University Hospital, Valladolid, Spain
  • Jay S Duker
    New England Eye Center, Tufts Medical Center, Boston, Massachusetts, United States
  • Jose María Ruiz-Moreno
    Universidad de Castilla-La Mancha, Albacete, Spain
  • Footnotes
    Commercial Relationships   Jorge Ruiz-Medrano, None; Marcos Rubio Caso, None; Ignacio Flores-Moreno, None; Pablo Peña-Garcia, None; Javier Montero, None; Jay Duker, None; Jose María Ruiz-Moreno, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 2184. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to Subscribers Only
      Sign In or Create an Account ×
    • Get Citation

      Jorge Ruiz-Medrano, Marcos Javier Rubio Caso, Ignacio Flores-Moreno, Pablo Peña-Garcia, Javier Montero, Jay S Duker, Jose María Ruiz-Moreno; Analysis of age-related Choroidal Layers thinning in Healthy Eyes Using Swept-Source Optical Coherence Tomography.. Invest. Ophthalmol. Vis. Sci. 2016;57(12):2184.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : To study the changes in the choroidal layers thickness with age in a healthy population using swept-source optical coherence tomography (SS-OCT).

Methods : Retrospective data analysis of a subgroup of eyes from a previous single-center, prospective, cross-sectional, non-interventional study. 169 healthy eyes were evaluated using SS-OCT. Inclusion criteria were best-corrected visual acuity between 20/20 and 20/25, spherical equivalent between ±3 diopters, and no systemic or ocular diseases. Two independent investigators determined the macular horizontal Choroidal Thickness (CT) and the Haller’s layer thickness across a 9 mm line centered at the fovea. Subjects were divided into five age groups.

Results : Mean subfoveal CT (SFCT) was 305.76±80.59 μm (95% confidence interval (CI): 294.85 to 319.33). Mean subfoveal thickness for Haller’s layer was 215.47±67.70 μm (95% CI: 207.30 to 227.86) and mean subfoveal thickness for choriocapillaris plus Sattler’s layer was 87.31±40.40 μm (95% CI: 83.38 to 95.65). No significant differences were found due to gender. CT profile was similar between groups with CT and Haller’s layer thickness decreasing with age (p=0.002).

Conclusions : Choroidal and Haller’s layer thickness profiles are similar between different age groups. Age-related choroidal thinning is mostly at the expense of Haller’s layer.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×