September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Methicillin-Resistant Staphylococcus Keratitis in a Referral Ophthalmology Center
Author Affiliations & Notes
  • Ismael Ávila-Lule
    Asociación para Evitar la Ceguera en México. Hospital "Dr. Luis Sánchez Bulnes", Mexico City, Mexico
  • Alfredo Terán-Tejada
    Cornea and Refractive Surgery, Asociación para Evitar la Ceguera en México, Hospital "Dr. Luis Sánchez Bulnes", Mexico City, Mexico
  • Nallely Ramos Betancourt
    Cornea and Refractive Surgery, Asociación para Evitar la Ceguera en México, Hospital "Dr. Luis Sánchez Bulnes", Mexico City, Mexico
  • Josué David Rodríguez-Pedraza
    Cornea and Refractive Surgery, Asociación para Evitar la Ceguera en México, Hospital "Dr. Luis Sánchez Bulnes", Mexico City, Mexico
  • Francisco Beltrán-Díaz De La Vega
    Cornea and Refractive Surgery, Asociación para Evitar la Ceguera en México, Hospital "Dr. Luis Sánchez Bulnes", Mexico City, Mexico
  • Everardo Hernandez-Quintela
    Cornea and Refractive Surgery, Asociación para Evitar la Ceguera en México, Hospital "Dr. Luis Sánchez Bulnes", Mexico City, Mexico
  • Footnotes
    Commercial Relationships   Ismael Ávila-Lule, None; Alfredo Terán-Tejada, None; Nallely Ramos Betancourt, None; Josué Rodríguez-Pedraza, None; Francisco Beltrán-Díaz De La Vega, None; Everardo Hernandez-Quintela, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 2354. doi:
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      Ismael Ávila-Lule, Alfredo Terán-Tejada, Nallely Ramos Betancourt, Josué David Rodríguez-Pedraza, Francisco Beltrán-Díaz De La Vega, Everardo Hernandez-Quintela; Methicillin-Resistant Staphylococcus Keratitis in a Referral Ophthalmology Center. Invest. Ophthalmol. Vis. Sci. 2016;57(12):2354.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate the frequency of Methicillin-Resistant Staphylococcus (MRS) Keratitis in a referral Ophthalmology Center in Mexico City.

Methods : A retrospective, observational study was performed. Data was collected from medical charts of patients who attended from February 2014 to February 2015 with diagnosis of infectious keratitis and positive cuture for Staphylococcus spp. The data base was subsequently used to obtain basic demographic information and results of gram stains, bacterial cultures, sensitivity and, resistance to antibiotics. MRS were identified by being resistant to oxacillin and/or cefoxitin disk diffusion.

Results : Two hundred-ninety four Staphylococcus spp were isolated from 294 patients with keratitis during the study period. A hundred-twenty six (42.9%) were methicillin resistant by oxacillin disk, and 55 (18.7%) by cefoxitin disk. The MRS isolates included S. epidermidis (n= 148), S. aureus (n=60), S. Haemolyticus (n=21), S. Saprophyticus (n=19), S. hominis (n= 13), S. intermedius (n=8), and others. The MRS corneal isolates displayed extensive antimicrobial resistance.

Conclusions : The emergence of Methicillin-resistant Staphylococcus strains is clinically relevant because their resistance to multiple antibiotics limits their treatment options. Moreover, the antibiotic susceptibility is decreasing, introducing new challenges regarding its treatment and making constant antibiotic surveillance a priority

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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