September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Conjunctival Tumors in Children. Analysis of 807 cases.
Author Affiliations & Notes
  • Kareem Sioufi
    Ocular Oncology, Wills Eye, Philadelphia, Pennsylvania, United States
  • Rizwan Alvi
    Ocular Oncology, Wills Eye, Philadelphia, Pennsylvania, United States
  • Adel Alset
    Ocular Oncology, Wills Eye, Philadelphia, Pennsylvania, United States
  • Emil Say
    Ocular Oncology, Wills Eye, Philadelphia, Pennsylvania, United States
  • Jerry A Shields
    Ocular Oncology, Wills Eye, Philadelphia, Pennsylvania, United States
  • Carol L Shields
    Ocular Oncology, Wills Eye, Philadelphia, Pennsylvania, United States
  • Footnotes
    Commercial Relationships   Kareem Sioufi, None; Rizwan Alvi, None; Adel Alset, None; Emil Say, None; Jerry Shields, None; Carol Shields, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 2402. doi:
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      Kareem Sioufi, Rizwan Alvi, Adel Alset, Emil Say, Jerry A Shields, Carol L Shields; Conjunctival Tumors in Children. Analysis of 807 cases.. Invest. Ophthalmol. Vis. Sci. 2016;57(12):2402.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To report the spectrum and frequency of conjunctival tumors in children.

Methods : A retrospective noninterventional case series of patients younger than 21 years of age was conducted to obtain clinical tumor features and diagnosis.

Results : Of 807 cases, the tumors were broadly classified as melanocytic in 551 (68%) and nonmelanocytic in 256 (32%). The nonmelanocytic categories included choristomatous (n=65 [8%]), epithelial (n=13 [2%]), vascular (n=55 [7%]), fibrous (n=4 [<1%]), neural (n=1 [<1%]), xanthomatous (n=7 [1%]), myxomatous (n=1 [<1%]), lipomatous (n=3 [<1%]), lacrimal gland origin (n=1 [<1%]), lymphoid (n=46 [6%]), secondary tumors (n=2 [<1%]), inflammatory/infectious (n = 37 [5%]), degenerative (n=2 [<1%]), and non-neoplastic lesions resembling tumor (n=19 [2%]). Of the 551 melanocytic lesions, the specific tumor diagnosis was nevus (n=489 [89%]), melanoma (n=19 [3%]), and primary acquired melanosis (n=27 [5%]). The most frequent symptom at time of presentation was a visible lesion on the eye (n=663 [82%] or localized redness (n=94 [12%]). Mean age at presentation was 11.4 years (median 11.4, range 0-21 years).

Conclusions : In children, conjunctival tumors were melanocytic in 68% and nonmelanocytic in 32% of cases. Overall, the top 5 diagnoses included conjunctival nevus, choristoma (dermolipoma/dermoid), vascular (lymphangioma/hemangioma), lymphoid, and inflammatory/infectious lesions.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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