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Kareem Sioufi, Rizwan Alvi, Adel Alset, Emil Say, Jerry A Shields, Carol L Shields; Conjunctival Tumors in Children. Analysis of 807 cases.. Invest. Ophthalmol. Vis. Sci. 2016;57(12):2402.
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© 2017 Association for Research in Vision and Ophthalmology.
To report the spectrum and frequency of conjunctival tumors in children.
A retrospective noninterventional case series of patients younger than 21 years of age was conducted to obtain clinical tumor features and diagnosis.
Of 807 cases, the tumors were broadly classified as melanocytic in 551 (68%) and nonmelanocytic in 256 (32%). The nonmelanocytic categories included choristomatous (n=65 [8%]), epithelial (n=13 [2%]), vascular (n=55 [7%]), fibrous (n=4 [<1%]), neural (n=1 [<1%]), xanthomatous (n=7 [1%]), myxomatous (n=1 [<1%]), lipomatous (n=3 [<1%]), lacrimal gland origin (n=1 [<1%]), lymphoid (n=46 [6%]), secondary tumors (n=2 [<1%]), inflammatory/infectious (n = 37 [5%]), degenerative (n=2 [<1%]), and non-neoplastic lesions resembling tumor (n=19 [2%]). Of the 551 melanocytic lesions, the specific tumor diagnosis was nevus (n=489 [89%]), melanoma (n=19 [3%]), and primary acquired melanosis (n=27 [5%]). The most frequent symptom at time of presentation was a visible lesion on the eye (n=663 [82%] or localized redness (n=94 [12%]). Mean age at presentation was 11.4 years (median 11.4, range 0-21 years).
In children, conjunctival tumors were melanocytic in 68% and nonmelanocytic in 32% of cases. Overall, the top 5 diagnoses included conjunctival nevus, choristoma (dermolipoma/dermoid), vascular (lymphangioma/hemangioma), lymphoid, and inflammatory/infectious lesions.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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