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Laura Alejandra González-Dibildox, Josué David Rodríguez-Pedraza, Nallely Ramos Betancourt, Abelardo Rodríguez-Reyes, Alfredo Terán-Tejada, Francisco Beltrán-Díaz De La Vega, Everardo Hernandez-Quintela; Melanocytic Conjunctival Lesions in a High Referral Ophthalmology Center in Mexico City. Invest. Ophthalmol. Vis. Sci. 2016;57(12):2403.
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© ARVO (1962-2015); The Authors (2016-present)
To describe the epidemiology, clinical and, histological features of melanocytic lesions in a single High Referral Ophthalmology Center in Mexico City.
The records of the Department of Ocular Pathology from 2005 to 2015 were reviewed. The search included corneal and/or conjunctival specimens containing the terms "melanoma", "nevus" and "primary acquired melanosis" (PAM), in the diagnosis. A total of 139 specimens were identified. Only initial biopsies were included. Pathology reports and corresponding clinical records were reviewed for patient age and gender, involved eye, location of the lesion, self- reported progression time, presumptive and definitive diagnosis, tumor grade, presence at surgical margins, corneal or intraocular invasion, mytotic activity and, rate of recurrence. Statistical analysis was performed using SPSS V. 22.
Mean age of patients was 30.4 years old (+/-21.8), and 76 (54.7%) were female. Right eye was affected in 77 cases (55.4%). Of 139 specimens included, 112 (80,6%) were classified as nevus without atypia, 3 (2,2%) nevus with atypia, 6 (3.6%) PAM without atypia, 5 (3.6%) PAM with atypia and 13 (9.4%) melanoma. Two (1.4%) eyes with melanoma had intraocular invasion.
Melanocytic lesions of conjunctiva are frequent. Most of cases were benign, but there was a considerable number of premalingmant lesions. Melanoma was present in almost 10% of the lesions in our Center.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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