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Hiroaki Ozaki, Jane Huang, Koji Murata, Ikuko Nata, Eiichi Uchio; Prevalence of glaucoma in retinal vein occlusion. Invest. Ophthalmol. Vis. Sci. 2016;57(12):2617.
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© 2017 Association for Research in Vision and Ophthalmology.
Systemic medical conditions of hypertension, hyperlipidemia, diabetes mellitus, smoking habits, and plasma viscosity abnormalities are known to be the etiology of retinal vein occlusion (RVO). Ocular conditions such as intraocular pressure (IOP), glaucoma, retinal circulation, disc size, axial lengths, and hypermetropia have also been reported to be associated to RVO. Japan has the highest incidence reported of both RVO and glaucoma as separate diseases.Our purpose is to to determine the prevalence of glaucoma in RVO patients from our institution and to compare the prevalence with the POAG in The Tajimi study.
We included 480 patients 489 eyes with RVO from November, 2008 to December, 2014. RVO was diagnosed based on color fundus photographs and fluorescein angiography at the initial visit. Clinical records included patients’ age, gender, and type of RVO. Initial RVO episode was recorded and must be within the last six months. The study excluded all eyes undergone panretinal photocoagulation, vitrectomy, or glaucoma filtration surgeries. We subdivided RVO into branch RVO (BRVO), hemicentral RVO (HRVO), and central RVO (CRVO) and divided glaucoma into primary open angle glaucoma (POAG), neovascular glaucoma (NVG), and primary angle closure glaucoma (PACG). The prevalence of glaucoma in each age group was analyzed and compared with The Tajimi Study. Age, gender, refractive error, and intraocular pressure (IOP) factors were investigated between RVO with POAG and without POAG.
A total 489 eyes (221 men and 268 women) were diagnosed as RVO. The mean age was 63.5±13.0. There were 345 eyes of BRVO, 14 eyes of HRVO, and 130 eyes of CRVO. The overall prevalence of glaucoma was 59/489 (12.1%). POAG was found in 43/345 (12.4%) eyes in BRVO, 4/14 (28.6%) in HRVO,and 11/130 (8.5%) in CRVO. PACG was found in two eyes in BRVO. NVG occurred in 22 eyes with 19 eyes in the CRVO group. The prevalence of POAG increased after 50 years old. Eighty years old or older had the most prevalence of POAG in all RVO groups. There were no significant differences in age, gender, RVO types, refractive error, or IOPs between RVO with POAG and RVO without POAG.
Consistent with other Caucasian population studies, older age was associated with both RVO and RVO with POAG. A high incidence of POAG was observed in patients with RVO.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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