September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Difference in tear meniscus between conjunctivochalasis eyes and normal eyes using anterior segment optical coherence tomography.
Author Affiliations & Notes
  • Kanako Kimura
    Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Eiheiji, Yoshida, Fukui, Japan
  • Yoshihiro Takamura
    Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Eiheiji, Yoshida, Fukui, Japan
  • Makoto Gozawa
    Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Eiheiji, Yoshida, Fukui, Japan
  • Satoshi Yokota
    Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Eiheiji, Yoshida, Fukui, Japan
  • Takehiro Matsumura
    Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Eiheiji, Yoshida, Fukui, Japan
  • Masaru Inatani
    Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Eiheiji, Yoshida, Fukui, Japan
  • Footnotes
    Commercial Relationships   Kanako Kimura, None; Yoshihiro Takamura, None; Makoto Gozawa, None; Satoshi Yokota, None; Takehiro Matsumura, None; Masaru Inatani, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 2836. doi:
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      Kanako Kimura, Yoshihiro Takamura, Makoto Gozawa, Satoshi Yokota, Takehiro Matsumura, Masaru Inatani; Difference in tear meniscus between conjunctivochalasis eyes and normal eyes using anterior segment optical coherence tomography.. Invest. Ophthalmol. Vis. Sci. 2016;57(12):2836.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To quantify the difference in the tear meniscus between conjunctivochalasis eyes and normal eyes using anterior segment optical coherence tomography (AS-OCT).

Methods : Twenty-two conjunctivochalasis subjects (conjunctivochalasis group) and 22 normal subjects (control group) were enrolled at the University of Fukui Hospital, Japan. The tear meniscus area (TMA) and the tear meniscus height (TMH) as measured using AS-OCT were compared between the two groups. Among the conjunctivochalasis group, potential relationships between TMA or TMH and fluorescein film tear breakup time, fluorescein staining score, and the extent of conjunctivochalasis was also evaluated.

Results : The conjunctivochalasis group had a significantly reduced TMA (P = 0.01) and larger TMH (P < 0.0001) than the control group. Although the control group exhibited a significantly positive correlation between TMA and TMH (r = 0.668, P = 0.001), the conjunctivochalasis group showed no significant correlation between TMA and TMH (r = 0.330, P = 0.133). In the conjunctivochalasis group, there was a positive correlation between TMA and fluorescein film tear breakup time (r = 0.529, P = 0.011), a negative correlation between TMA and fluorescein staining score (r = −0.587, P = 0.004), and a positive correlation between TMH and the extent of conjunctivochalasis (r = 0.448, P = 0.021).

Conclusions : Conjunctivochalasis eyes exhibit a reduced TMA and increased TMH compared to normal eyes. A more severe dry eye condition in conjunctivochalasis is associated with a reduced TMA despite having a high TMH due to the conjunctival fold.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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