September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Sleep disturbance is associated with dry eye syndrome in a rural population in Korea : Study group for Environmental Eye Disease (SEED)
Author Affiliations & Notes
  • Hyungseon Yeom
    Department of Preventive Medicine, Yonsei University School of Medicine, Seoul, Korea (the Republic of)
  • Na Hyun Kim
    Department of Public Health, Yonsei University Graduate School, Seoul, Korea (the Republic of)
  • Jong Suk Song
    Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea (the Republic of)
  • Hyung Keun Lee
    Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea (the Republic of)
  • Hyeon Chang Kim
    Department of Preventive Medicine, Yonsei University School of Medicine, Seoul, Korea (the Republic of)
  • Footnotes
    Commercial Relationships   Hyungseon Yeom, None; Na Hyun Kim, None; Jong Suk Song, None; Hyung Keun Lee, None; Hyeon Chang Kim, None
  • Footnotes
    Support  This work was supported by a grant from the Korean Health Technology R&D Project, Ministry of Health & Welfare, Korea (HI13C0055).
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 2839. doi:
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      Hyungseon Yeom, Na Hyun Kim, Jong Suk Song, Hyung Keun Lee, Hyeon Chang Kim; Sleep disturbance is associated with dry eye syndrome in a rural population in Korea : Study group for Environmental Eye Disease (SEED). Invest. Ophthalmol. Vis. Sci. 2016;57(12):2839.

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      © 2017 Association for Research in Vision and Ophthalmology.

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Abstract

Purpose : To evaluate the association between sleep disturbance and dry eye syndrome (DES).

Methods : We conducted a cross-sectional survey of 437 (160 men and 277 women) participants who live in a rural island in Korea. The mean age of the participants was 65 years (range 43 to 92). We assessed their health status by a questionnaire, physical examinations and blood tests. Presence of DES was defined as Ocular Surface Disease Index score ≥ 13 points. Sleep disturbance was defined as having difficulty more than once a week either in falling asleep or in going back to sleep when awoken during night. Multiple logistic regression was used to analyze the association after adjusting for age, hypertension, diabetes, dyslipidemia, body mass index, smoking, alcohol drinking, exercise, menopause and sleep duration. All analyses were separated by sex.

Results : The prevalence of sleep disturbance was 35.6% in men and 53.8% in women. The prevalence of DES was 26.9% in men and 48.0% in women. The unadjusted odds ratio (95% CI) of sleep disturbance according to the presence of DES was 3.21 (1.56 - 6.63) in men and 1.74 (1.08 - 2.82) in women. After adjusting other covariates the adjusted odds ratio (95% CI) was 3.04 (1.28 - 7.26) in men and 1.78 (1.08 - 2.92) in women.

Conclusions : Our findings suggest that sleep disturbance is associated with presence of DES in rural population. Further prospective study is required to reveal the causal relationship.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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