September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Functional And Anatomical Modifications In A Six-Month Follow-up Of Patients Treated With Collagen Cross-linking.
Author Affiliations & Notes
  • Riccardo Scotto
    DiNOGMI, University of Genoa, Genova, Italy
  • Donatella Musetti
    DiNOGMI, University of Genoa, Genova, Italy
  • Fabio Licata
    DiNOGMI, University of Genoa, Genova, Italy
  • Carlo Enrico Traverso
    DiNOGMI, University of Genoa, Genova, Italy
  • Footnotes
    Commercial Relationships   Riccardo Scotto, None; Donatella Musetti, None; Fabio Licata, None; Carlo Traverso, None
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 2916. doi:
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      Riccardo Scotto, Donatella Musetti, Fabio Licata, Carlo Enrico Traverso; Functional And Anatomical Modifications In A Six-Month Follow-up Of Patients Treated With Collagen Cross-linking.. Invest. Ophthalmol. Vis. Sci. 2016;57(12):2916.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To analyze functional and anatomical corneal changes after corneal collagen cross-linking.

Methods : 41 eyes of 35 patients (25 male and 10 female) mean age 24 ±7 years affected by mono or bilateral progressive keratoconus were enrolled. All patients underwent corneal collagen cross-linking using epithelium-off technique. Corneal topography, anterior segment OCT and in-vivo confocal microscopy were used for the evaluation of corneal changes.

Results : Compared to pre-treatment values, corneal curvature and corneal apex decreased (p>0,05), Best Corrected Visual Acuity (BCVA) improved from 20/32 to 20/25 (p<0,05), while Central Corneal Thickness (CCT) was unchanged at 6-month follow-up visit (p=0,9557). In-vivo confocal microscopy showed anatomical changes during follow-up.

Conclusions : Our study highlights that corneal anatomical changes have led to improved visual function. This confirms the efficacy and safety of collagen cross-linking in patients with progressive keratoconus.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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