September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Trans-Epithelial Accelerated Corneal Cross-linking for Keratoconus in Children: 18 month follow-up
Author Affiliations & Notes
  • Alejandro Navas
    Instituto de Oftalmologia - Catarata, Institute of Ophthalmology "Conde de Valenciana", Mexico City, DF, Mexico
  • Andrew Olivo-Payne
    Instituto de Oftalmologia - Catarata, Institute of Ophthalmology "Conde de Valenciana", Mexico City, DF, Mexico
  • Alexandra Abdala
    Instituto de Oftalmologia - Catarata, Institute of Ophthalmology "Conde de Valenciana", Mexico City, DF, Mexico
  • Erick Hernandez-Bogantes
    Instituto de Oftalmologia - Catarata, Institute of Ophthalmology "Conde de Valenciana", Mexico City, DF, Mexico
  • Arturo J Ramirez-Miranda
    Instituto de Oftalmologia - Catarata, Institute of Ophthalmology "Conde de Valenciana", Mexico City, DF, Mexico
  • Enrique O Graue-Hernandez
    Instituto de Oftalmologia - Catarata, Institute of Ophthalmology "Conde de Valenciana", Mexico City, DF, Mexico
  • Footnotes
    Commercial Relationships   Alejandro Navas, None; Andrew Olivo-Payne, None; Alexandra Abdala, None; Erick Hernandez-Bogantes, None; Arturo Ramirez-Miranda, None; Enrique Graue-Hernandez, None
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 2917. doi:
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    • Get Citation

      Alejandro Navas, Andrew Olivo-Payne, Alexandra Abdala, Erick Hernandez-Bogantes, Arturo J Ramirez-Miranda, Enrique O Graue-Hernandez; Trans-Epithelial Accelerated Corneal Cross-linking for Keratoconus in Children: 18 month follow-up. Invest. Ophthalmol. Vis. Sci. 2016;57(12):2917.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate the safety and efficacy of trans-epithelial accelerated corneal cross-linking (TE-ACXL) in children with progressive keratoconus.

Methods : Prospective, consecutive, case-series of 23 eyes of 14 children who underwent TE-ACXL. Tomographic and refractive changes were analyzed at baseline and 1, 3, 6, 12 and 18 months postoperatively.

Results : Follow-up ranged from 18 to 30 months with a mean follow-up time of 23.82 months ±3.15. Mean age was 13.7 years ±1.4 (range 11-16). Mean preoperative UDVA from 0.92 ± 0.45 logMAR (20/160) to 0.71 ± 0.40 logMAR (20/100) (p=0.001). Mean keratometry (Km) changed from 53.87 ± 6.03 to 53.00 ± 5.81 (p=0.001). Pachymetry was 433.64±38.09 microns before treatment and 430.09 ± 54.26 microns at last follow-up (p=0.30). The mean preoperative sphere was -5.58±2.48 D and -4.89±4.66 (p=0.11) at last follow-up; refractive cylinder and spherical equivalent from -5.58±2.48 to -5.02±2.23 (p=0.046) and -7.90±5.39 to -7.41±4.84 (0.043), respectively.

Conclusions : Tomographic and refractive stability was shown in over 91% of eyes with progressive keratoconus who underwent TE-ACXL

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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