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Thomas Williams, Donny Suh; Assessment of the plusoptiX A12 photoscreener to detect amblyogenic risk factors in Nebraska. Invest. Ophthalmol. Vis. Sci. 2016;57(12):3097.
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© ARVO (1962-2015); The Authors (2016-present)
To determine the accuracy of the plusoptiX A12 photoscreener (PPS) in detecting amblyopia or ambylogenic risk factors in pediatric patients of Nebraska.
Using the PPS, we collected data from children seen at a single pediatric ophthalmology practice over the course of a 3-month period. Each patient was screened using the device and received a comprehensive ophthalmic examination. The results of the PPS were compared to the gold standard, comprehensive ophthalmic examination findings. The assessment of amblyopia or amblyogenic risk factors in our patients were based on the updated American Association for Pediatric Ophthalmology and Strabismus (AAPOS) referral criteria guidelines.
Data was collected from 219 children (438 eyes) during the 3-month study period. Among these, 87 children (40%) were determined to have amblyopia or ambylogenic risk factors after the comprehensive pediatric ophthalmology examination on the basis of the AAPOS guidelines. We found the plusoptiX A12 to have a sensitivity of 93.02%, specificity of 84.96%, false positive rate of 9.13%, false negative rate of 2.74%, positive predictive value of 80.00%, and negative predictive value of 94.96%.
PPS is a viable option and is comparable to various commercially available devices to detect refractive amblyogenic risk factors based on Nebraska pediatric patient population. While the results of this outpatient clinic are promising, our sample had a higher incidence of amblyopia than the general population due to partial selection bias. Future studies may show increased sensitivity by combining the use of the plusoptiX A12 with an alternate cover test.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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