September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Peripapillary Choroidal Thickness Change of Polypoidal Choroidal Vasculopathy after Anti-Vascular Endothelial Growth Factor Treatment
Author Affiliations & Notes
  • Kyou Ho Lee
    Ophthalmology, Severance hospital, Yonsei University, Seoul, Korea (the Republic of)
  • Ji Min Lee
    Ophthalmology, Severance hospital, Yonsei University, Seoul, Korea (the Republic of)
  • Footnotes
    Commercial Relationships   Kyou Ho Lee, None; Ji Min Lee, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 3364. doi:
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    • Get Citation

      Kyou Ho Lee, Ji Min Lee; Peripapillary Choroidal Thickness Change of Polypoidal Choroidal Vasculopathy after Anti-Vascular Endothelial Growth Factor Treatment. Invest. Ophthalmol. Vis. Sci. 2016;57(12):3364.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To investigate peripapillary choroidal thickness (PCT) of polypoidal choroidal vasculopathy (PCV) and exudative age-related macular degeneration (AMD), and to evaluate their responses to anti-vascular endothelial growth factor (VEGF).

Methods : Thirty eyes with PCV and 25 eyes with exudative AMD who were treatment naive were included in the study. PCT and subfoveal choroidal thickness (CT) were evaluated before and after intravitreal anti-VEGF.

Results : The initial mean PCT of PCV (153.78 ± 56.23 μm) was thicker than that of exudative AMD (88.77 ± 23.11 μm, P < 0.001). Temporal, superior, nasal, and inferior PCT of PCV were all thicker than exudative AMD (all, P < 0.05). After anti-VEGF, the mean PCT of PCV was significantly reduced (134.17 ± 41.66 μm, P < 0.001) but not in exudative AMD (86.87 ± 22.54 μm, P =0.392). PCT in each quadrant showed a similar tendency.

Conclusions : PCV exhibit a thick choroid overall in both the peripapillary and macula regions. Both regions decrease in thickness after anti-VEGF in PCV, but not in exudative AMD. In exudative AMD, subfoveal CT decreased but the peripapillary region did not.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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