September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
The Effect of Mitomycin C in Recurrent Pterygium Surgery with Amniotic Membrane Transplantation
Author Affiliations & Notes
  • Byung Yi Ko
    Ophthalmology, Konyang University College of Medicine and Hospital, Daejeon, Korea (the Republic of)
  • Kyu Jin Han
    Ophthalmology, Konyang University College of Medicine and Hospital, Daejeon, Korea (the Republic of)
  • Footnotes
    Commercial Relationships   Byung Yi Ko, None; Kyu Jin Han, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 3489. doi:
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      Byung Yi Ko, Kyu Jin Han; The Effect of Mitomycin C in Recurrent Pterygium Surgery with Amniotic Membrane Transplantation. Invest. Ophthalmol. Vis. Sci. 2016;57(12):3489.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : We performed a retrospective, observational clinical study to compare postoperative recurrence and symblepharon following excision of recurrent pterygium combined with amniotic membrane transplantation (AMT) according to intraoperative mitomycin C (MMC) application.

Methods : An analysis of 20 eyes of 19 patients who underwent recurrent pterygium surgery with AMT. Eight eyes received MMC intraoperatively, while the other 12 eyes did not. Recurrence rates and complications were evaluated.

Results : Mean postoperative follow up was 19.8 months. Conjunctival recurrences were noted in 2 eyes and corneal recurrences were found in 3 eyes in AMT with MMC group (62.5%). Conjunctival recurrences were noted in 3 eyes and corneal recurrences were found in 4 eyes in AMT without MMC group (58.3%). There was no significant difference in recurrence rates (p = 0.91). In cases with preoperative symblepharon, symblepharon did not recur postoperatively in eyes with MMC, but postoperative symblepharons were noted in eyes without MMC. There was no significant complication in both groups.

Conclusions : The application of MMC was effective to prevent recurrent symblepharon, but had no significant effect on recurrence rates in excision of recurrent pterygium with AMT.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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