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Jianhua Cang; Direction Selectivity in the Mouse Superior Colliculus. Invest. Ophthalmol. Vis. Sci. 201657(12):.
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© 2017 Association for Research in Vision and Ophthalmology.
Presentation Description :
Visual information is first processed in the retina where different subtypes of retinal ganglion cells (RGCs) encode specific features of the visual scene. The signals encoded by RGC subtypes are further integrated and transformed in various retinal targets in the brain to give rise to specific visual response properties. Recently, mouse has become a useful model in vision research due to the technical advances in genetic, imaging, and physiological methodologies. In mice, more than 70% RGCs project to the superior colliculus (SC), a midbrain structure important for multimodal integration and sensorimotor transformation. The significance of the SC in mouse vision thus makes it an important system to study visual transformation and its underlying mechanisms. In this talk, I will present our recent discoveries of visual response properties in the mouse SC and our ongoing effort to study retinocollicular transformation, with a focus on the processing of motion direction.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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