September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Total, corneal and ocular residual astigmatism: Distribution in a German population and age-dependency – The Gutenberg Health Study
Author Affiliations & Notes
  • Alexander Karl-Georg Schuster
    University Medical Center Mainz, Department of Ophthalmology, Mainz, Germany
  • Norbert Pfeiffer
    University Medical Center Mainz, Department of Ophthalmology, Mainz, Germany
  • Andreas Schulz
    Preventive Cardiology and Preventive Medicine / Center for Cardiology, University Medical Center Mainz, Mainz, Germany
  • René Hoehn
    University Medical Center Mainz, Department of Ophthalmology, Mainz, Germany
    Department of Ophthalmology, Inselspital, Bern, Switzerland
  • Katharina A Ponto
    University Medical Center Mainz, Department of Ophthalmology, Mainz, Germany
    Center for Thrombosis and Hemostasis (CTH), University Medical Center, Mainz, Germany
  • Maria Blettner
    Institute for Medical Biostatistics, Epidemiology and Informatics, University Medical Center Mainz, Mainz, Germany
  • Philipp S Wild
    Preventive Cardiology and Preventive Medicine / Center for Cardiology, University Medical Center Mainz, Mainz, Germany
    Center for Thrombosis and Hemostasis (CTH), University Medical Center, Mainz, Germany
  • Alireza Mirshahi
    University Medical Center Mainz, Department of Ophthalmology, Mainz, Germany
    Dardenne Eye Clinics, Bonn, Germany
  • Footnotes
    Commercial Relationships   Alexander Schuster, None; Norbert Pfeiffer, None; Andreas Schulz, None; René Hoehn, None; Katharina Ponto, None; Maria Blettner, None; Philipp Wild, None; Alireza Mirshahi, None
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 3981. doi:
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      Alexander Karl-Georg Schuster, Norbert Pfeiffer, Andreas Schulz, René Hoehn, Katharina A Ponto, Maria Blettner, Philipp S Wild, Alireza Mirshahi; Total, corneal and ocular residual astigmatism: Distribution in a German population and age-dependency – The Gutenberg Health Study. Invest. Ophthalmol. Vis. Sci. 2016;57(12):3981.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Worldwide, the most frequent cause of visual impairment is uncorrected refractive error. This study focused on the distribution of total, corneal and ocular residual astigmatism in a German population and evaluated associated factors for each of the three types of astigmatisms.

Methods : A population-based cross-sectional study was performed in a German population as part of the Gutenberg Health Study. A comprehensive ophthalmological examination including refraction, tonometry, Scheimpflug imaging of the anterior cornea (Pachycam, Oculus, Wetzlar, Germany) was performed. In addition to the magnitude and type (with-the-rule, against-the-rule, oblique) of total and corneal astigmatism we calculated the vector components (J0, J45) of both astigmatisms and computed ocular residual astigmatism. Associations of the vector components were analyzed with Spearman Rank-correlations. We performed multiple quantile regression analysis to evaluate associated factors on total, corneal and ocular residual astigmatisms

Results : 13558 subjects (49% female) with a mean age of 54.0 +/- 9.0 years (range 35 to 74 years) were included in this study. The distribution of total astigmatism showed a two-peak distribution having high astigmatism in with-the-rule and against-the-rule position. Corneal astigmatism especially had high astigmatism at with-the-rule position, while ocular residual had a peak at against-the rule position. Associated factors were keratometry, age and sex for the different astigmatisms (p<0.001). Total astigmatism increased with age and women showed less astigmatism, while corneal astigmatism was lower in older subjects and in men.

Conclusions : In a large German cohort we found a shift from with-the-rule astigmatism to against-the-rule astigmatism for total astigmatism with age. With-the-rule astigmatism was primarily associated by corneal astigmatism while high amount of against-the-rule astigmatism was due to ocular residual astigmatism.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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