September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Effects of Small-Incision Lenticule Extraction (SMILE) on Corneal Endothelial Cells
Author Affiliations & Notes
  • Jesus Cabral
    Cornea and Refractive Surgery, Instituto de Oftalmología, Fundación Conde de Valenciana, Mexico City, Mexico
  • Flor Daniela Guzman-Iturbe
    Cornea and Refractive Surgery, Instituto de Oftalmología, Fundación Conde de Valenciana, Mexico City, Mexico
  • Alejandro Navas
    Cornea and Refractive Surgery, Instituto de Oftalmología, Fundación Conde de Valenciana, Mexico City, Mexico
  • Aida Jimenez-Corona
    Cornea and Refractive Surgery, Instituto de Oftalmología, Fundación Conde de Valenciana, Mexico City, Mexico
  • Enrique O Graue-Hernandez
    Cornea and Refractive Surgery, Instituto de Oftalmología, Fundación Conde de Valenciana, Mexico City, Mexico
  • Arturo J Ramirez-Miranda
    Cornea and Refractive Surgery, Instituto de Oftalmología, Fundación Conde de Valenciana, Mexico City, Mexico
  • Footnotes
    Commercial Relationships   Jesus Cabral, None; Flor Daniela Guzman-Iturbe, None; Alejandro Navas, Alcon Laboratories, Inc. (C); Aida Jimenez-Corona, None; Enrique Graue-Hernandez, None; Arturo Ramirez-Miranda, Carl Zeiss Meditec (C)
  • Footnotes
    Support  NONE
Investigative Ophthalmology & Visual Science September 2016, Vol.57, No Pagination Specified. doi:
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      Jesus Cabral, Flor Daniela Guzman-Iturbe, Alejandro Navas, Aida Jimenez-Corona, Enrique O Graue-Hernandez, Arturo J Ramirez-Miranda; Effects of Small-Incision Lenticule Extraction (SMILE) on Corneal Endothelial Cells. Invest. Ophthalmol. Vis. Sci. 201657(12):.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To investigate the corneal endothelial changes after SMILE procedure.

Methods : Prospective study, a total of 30 eyes of 15 patients with myopia ranging from -3.25 to -10.00 diopters (D) and astigmatism up to -3.50D were treated with SMILE. Endothelial cell density (ECD), and the coefficient of variation (CV), were measured preoperatively and at 1 day and 3 months postoperatively.

Results : No eyes developed corneal edema or other complications. No significant changes were observed regarding ECD and CV at any visit point (p>0.05). Endothelial cell changes in terms of ECD, CV were not correlated with the amount of myopia or astigmatism.

Conclusions : SMILE showed improvement in visual acuity and no adverse effects to corneal endothelial cells were found.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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