September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Influence of contact lens wearing on whole corneal thickness and corneal epithelial thickness measured with Fourier-domain optical coherence tomography
Author Affiliations & Notes
  • Joanna Wasielica-Poslednik
    Dept. of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany
  • Marcel Sebastian Sievers
    Dept. of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany
  • Walter Lisch
    Dept. of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany
  • Veronika Weyer
    Institute for Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany
  • Norbert Pfeiffer
    Dept. of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany
  • Adrian Gericke
    Dept. of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany
  • Footnotes
    Commercial Relationships   Joanna Wasielica-Poslednik, None; Marcel Sievers, None; Walter Lisch, None; Veronika Weyer, None; Norbert Pfeiffer, None; Adrian Gericke, None
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 4360. doi:
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      Joanna Wasielica-Poslednik, Marcel Sebastian Sievers, Walter Lisch, Veronika Weyer, Norbert Pfeiffer, Adrian Gericke; Influence of contact lens wearing on whole corneal thickness and corneal epithelial thickness measured with Fourier-domain optical coherence tomography. Invest. Ophthalmol. Vis. Sci. 2016;57(12):4360.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To investigate the effect of contact lens use on whole corneal thickness (CT) and corneal epithelial thickness (ET) measured with Fourier-domain optical coherence tomography (FD-OCT, RTVue).

Methods : Both eyes of 17 soft contact lens (SCL) wearers, 9 hard contact lens (HCL) wearers and 31 age- and sex-matched controls were included in this prospective study. CT and ET were measured with FD-OCT in 9 areas: corneal vertex, 4 paracentral and 4 peripheral zones in control subjects and in CL-wearers immediately after discontinuing of CL. The second measurement was performed in controls and CL-wearers after five days of CL-discontinuation. At each visit, refraction error, best-corrected visual acuity, slit-lamp examination and Schirmer test were performed in both eyes of all subjects. Statistical analyses were conducted using ANOVA, Mann-Whitney test, t-test and Wilcoxon test.

Results : ET differed relevantly in vertex and in paracentral zones between the individual groups (HCL < SCL < controls, p<0.05) at baseline. After five days of CL restriction, an increase of ET in vertex and in paracentral zones was noted in the HCL-wearers (p<0.05), but not in the SCL-wearers and in the control group. CT did not differ relevantly between the study groups at baseline [HCL > control > SCL (p>0.05)]. Five days of contact lens restriction had no relevant influence on CT, BCVA, refraction error and Schirmer test.

Conclusions : ET was relevantly thinner in vertex and in corneal paracentral zones in CL wearers compared to controls. A five day discontinuation of CL wearing led to an increase in ET, which was relevant in HCL-wearers.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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