September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Myopic LASIK Visual Rehabilitation: Multicenter Analysis of Longitudinal Outcomes up to 1 year
Author Affiliations & Notes
  • Tarika Thareja
    Department of Ophthalmology, New York University School of Medicine, New York, New York, United States
  • George Asimellis
    LaserVision.gr Clinical & Research Eye Institute, Athens, Greece
  • Laurence T Sperber
    Department of Ophthalmology, New York University School of Medicine, New York, New York, United States
  • A. John Kanellopoulous
    LaserVision.gr Clinical & Research Eye Institute, Athens, Greece
    Department of Ophthalmology, New York University School of Medicine, New York, New York, United States
  • Footnotes
    Commercial Relationships   Tarika Thareja, None; George Asimellis, None; Laurence Sperber, None; A. John Kanellopoulous, Alcon/WaveLight (C), Allergan (C), Avedro (C), i-Optics (C), ISP Surgical (C), Keramed (C)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 4849. doi:
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      Tarika Thareja, George Asimellis, Laurence T Sperber, A. John Kanellopoulous; Myopic LASIK Visual Rehabilitation: Multicenter Analysis of Longitudinal Outcomes up to 1 year. Invest. Ophthalmol. Vis. Sci. 2016;57(12):4849.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Laser in situ keratomileusis (LASIK) is a safe, effective, and predictable surgical procedure for myopia correction. Recent advances in refractive laser platforms have been introduced. The purpose of this study is to report one-year visual rehabilitation results of myopic LASIK employing the Alcon/WaveLight Refractive Suite (FS200-femtosecond and EX500-Excimer lasers, Alcon Surgical, Ft.Worth, Tx).

Methods : Fifty-nine myopic eyes were subjected to femtosecond-laser assisted LASIK at two independent centers: one US-based (US n1 = 24 eyes) and one Europe-based (EU n2 = 35 eyes). Eleven eyes had myopia and 48 had myopia + astigmatism. Mean patient age was 33.3 +/- 9.22 years (19 to 60). The following assessments were performed pre-operatively (baseline) and post-operatively (PO): visual acuity (uncorrected – UDVA, best corrected – CDVA, both performed with EDTRS charts) and manifest refraction.

Results : Mean baseline refraction was -4.25 +/- 2.33D sphere (-12.00 to -0.25) and -0.95 +/- 0.85D cylinder (-4.0 to 0.0). For OD, mean baseline CDVA was -0.046 +/- 0.086 LogMAR. Post-operative UDVA was 0.043 +/- 0.147, -0.021 +/- 0.127, -0.024 +/- 0.112, -0.041 +/- 0.098, and -0.059 +/- 0.127 LogMAR at day 1, 1 month, 3 months, 6 months, and 12 months PO, respectively. For OS, mean baseline CDVA was -0.042 LogMAR. Post-operative UDVA was 0.038 +/- 0.118, -0.029 +/- 0.113, -0.027 +/- 0.113, -0.045 +/- 0.112, and -0.067 +/- 0.099 LogMAR, respectively. At 1 month, 59.3% of eyes had no change in CDVA, 22.0% of eyes gained 1 line, and 5.1% gained 2 lines. At 12 months, 35.6% of eyes had no change in CDVA, 50.0% of eyes gained 1 line, and 7.6% gained 2 lines. There was no statistically significant difference between the US and EU centers in any metric evaluated.

Conclusions : This study documents and confirms extensive myopic LASIK longitudinal outcome analysis indicating safety and efficacy from two independent centers.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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