September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Changes in anatomical parameters, visual performances and quality of vision after a LASIK refractive surgery.
Author Affiliations & Notes
  • Imene SALAH
    Laboratoire Aimé Cotton, CNRS, Université Paris-Sud, Univ. Paris-Saclay, Paris, France
    Anterior segment and refractive surgery, Fondation ophtalmologique Adolphe de Rothschild, Paris, France
  • Damien Gatinel
    Anterior segment and refractive surgery, Fondation ophtalmologique Adolphe de Rothschild, Paris, France
    CEROC: Center of Expertise and Research in Optics for Clinicians, Paris, France
  • Richard Legras
    Laboratoire Aimé Cotton, CNRS, Université Paris-Sud, Univ. Paris-Saclay, Paris, France
  • Footnotes
    Commercial Relationships   Imene SALAH, None; Damien Gatinel, None; Richard Legras, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 4851. doi:
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      Imene SALAH, Damien Gatinel, Richard Legras; Changes in anatomical parameters, visual performances and quality of vision after a LASIK refractive surgery.. Invest. Ophthalmol. Vis. Sci. 2016;57(12):4851.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate changes in anatomical parameters of the eye, visual performances and quality of vision after a LASIK refractive surgery performed with the WaveLight® Refractive Suite-ALCON® (Alcon Laboratories, Inc., Fort Worth, TX).

Methods : We examined 30 eyes of 15 myopic (average Spherical Equivalent of – 4.5D ranging from -8.5 to -0.75D) patients aged from 24 to 39 years. Anatomical parameters (pachymetry, corneal hysteresis (CH), resistance factor (CRF), Intra-Ocular Pressure (IOP), central keratometry, Q-factor, corneal and total aberrations on a 4.5 mm pupil), visual performances (high and low contrast visual acuity (VA), contrast sensitivity at 12 cycles per degree and tolerance to blur defined as the range of defocus for which high contrast letters of 20/50 was still perceived acceptable), dry eye assessment (Break Up Time (BUT), OSDI questionnaire) and quality of vision (QoV and Scale Ophthalmology questionnaire) were measured prior to the surgery and 1 day (D1), 1 month (M1) and 3 months (M3) after.

Results : Three months after surgery, keratometry became flatter and the Q-factor more positive (more oblate from-0.19±0.08 to+0.45±0.46). Both were significantly correlated (r2=0.7). CH, CRF and BUT significantly decreased respectively from 11.6±1.4mmHg (mean±SD) to 9.3±1.1mmHg, from 10.7±1.4mmHg to 7.5±1.4mmHg and from 9±1.6sec to 6.7±3.4sec at M3. Pachymetry decreased by 124±62.2µm at D1 and increased by 44±32.6µm between D1 and M3 probably due to epithelial remodelling. Refraction became hyperopic at D1 (+0.40±0.51D). At M3, refraction shifted to a less hyperopic value (+0.13±0.41D) whereas keratometry continued to decrease (from 40.77±1.94 to 40.5±2.02). Corneal refractive index and/or internal changes may explain this difference. The only significant high-order aberration change postoperatively was an increase of 3rd order coma. While corneal astigmatism significantly decreased from 0.85 to 0.55D, total astigmatism remained unchanged (from 0.41 to 0.33). Three months after surgery, high and low contrast VA were slightly (<0.05 logMAR) but significantly improved, whereas contrast sensitivity and tolerance to blur remained unchanged. Quality of vision was not affected by surgery.

Conclusions : Some corneal and/or internal changes arising between D1 and M3 may limit the amount of residual refractive error to finally provide a good vision 3 months after this refractive surgery.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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