September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Microperimetry and Fundus Photography in Patients with Drusen and/or Age-related Macular Degeneration
Author Affiliations & Notes
  • Michael Kapusta
    Ophthalmology, Sir Mortimer B. Davis Jewish General Hospital, Montreal, Quebec, Canada
    Ophthalmology, McGill University, Montreal, Quebec, Canada
  • Julie-Andree Marinier
    School of Optometry, University of Montreal, Montreal, Quebec, Canada
    Institut Nazareth et Louis-Braille, Montreal, Quebec, Canada
  • Pierre Forcier
    School of Optometry, University of Montreal, Montreal, Quebec, Canada
  • David Nguyen-Tri
    School of Optometry, University of Montreal, Montreal, Quebec, Canada
  • Caitlin Murphy
    School of Optometry, University of Montreal, Montreal, Quebec, Canada
  • Olga Overbury
    School of Optometry, University of Montreal, Montreal, Quebec, Canada
    Ophthalmology, Sir Mortimer B. Davis Jewish General Hospital, Montreal, Quebec, Canada
  • Footnotes
    Commercial Relationships   Michael Kapusta, None; Julie-Andree Marinier, None; Pierre Forcier, None; David Nguyen-Tri, None; Caitlin Murphy, None; Olga Overbury, None
  • Footnotes
    Support  This study is supported through a partnership among the Antoine-Turmel Foundation, the FRQS, and the RRSV
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 4980. doi:
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      Michael Kapusta, Julie-Andree Marinier, Pierre Forcier, David Nguyen-Tri, Caitlin Murphy, Olga Overbury; Microperimetry and Fundus Photography in Patients with Drusen and/or Age-related Macular Degeneration. Invest. Ophthalmol. Vis. Sci. 2016;57(12):4980.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : The relationship between drusen and pigmentary changes identified in fundus photos and the overlying retinal sensitivity has not been well studied. The purpose of this research was to compare macular drusen and pigment mottling, identified on fundus photos, to microperimetry of the macula conducted via optical coherence tomographer/scanning laser ophthalmoscope (OCT/SLO).

Methods : Patients over the age of 50 who had drusen or were diagnosed with AMD were recruited into the study. Visual acuity was measured with ETDRS charts. Colour fundus photos were taken and subsequently were graded using the Age-related Eye Disease Study (AREDS) grading criteria for AMD. Microperimetry was performed using the Optos OCT/SLO. Microperimetry images were scaled and superimposed over fundus photos.

Results : To date, this ongoing study demonstrates a trend of decreased macular sensitivity over areas of large and/or numerous drusen or pigment mottling. Many participants showed decreased macular sensitivity despite maintaining good visual acuity. Some participants classified as AREDS Category 1 on fundus photos showed microperimetry comparable to those in more advanced AREDS categories.

Conclusions : Retinal areas affected by drusen have decreased sensitivity despite good visual acuity and early AREDS-category placement. Microperimetry may be useful in early detection of AMD or identification of AMD patients who are more likely to advance to later stages. Visual acuity and fundus photos alone may indicate visual function to be better than it actually is. Combining microperimetry with fundus photo information can give clinicians and rehabilitation specialists a more accurate picture of a patient’s functional status.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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