September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Epidemiologic characteristics of giant cell arteritis using a national inpatient database
Author Affiliations & Notes
  • Natasha V Nayak
    Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, United States
  • Milap Raikundalia
    New Jersey Medical School, Rutgers University, Newark, New Jersey, United States
  • Jean Anderson Eloy
    New Jersey Medical School, Rutgers University, Newark, New Jersey, United States
  • Footnotes
    Commercial Relationships   Natasha Nayak, None; Milap Raikundalia, None; Jean Eloy, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 5082. doi:
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      Natasha V Nayak, Milap Raikundalia, Jean Anderson Eloy; Epidemiologic characteristics of giant cell arteritis using a national inpatient database. Invest. Ophthalmol. Vis. Sci. 2016;57(12):5082.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Giant cell arteritis (GCA) is a vasculitis associated with significant ocular and systemic morbidity. The possibility of seasonality of GCA, and the role of diabetes in this population are amongst recent topics of interest. Our purpose was to evaluate epidemiologic characteristics of giant cell arteritis using a national inpatient database.

Methods : The Nationwide Inpatient Sample database from 2002-2010 was utilized to analyze epidemiological characteristics of patients with giant cell arteritis in the United States. Patient demographics, time/length of stay, hospital charges, incidence of temporal artery biopsy, and concomitant diagnoses were analyzed

Results : 5,337 cases of giant cell arteritis were identified (mean age 74.4±11 years; 74% female). The number of cases varied by year, reaching a peak in 2003 (n=633) and a trough in 2010 (n=512). The number of cases by month peaked in August (n=459), and troughed in November (n=331). Temporal artery biopsy was performed in a majority of cases (53% unilateral, 3% bilateral). Diabetic GCA patients (n=1547, 30%) were significantly younger, more likely to be of non-Caucasian ethnicity, and had a longer length of stay (p<0.0001). Inpatient mortality was 7%. The most common noted cranial nerve palsy was of the sixth nerve (0.5%). Retinal artery occlusion was noted in rare cases (2.5%).

Conclusions : The Nationwide Inpatient Sample could be utilized to further understand the epidemiologic characteristics of giant cell arteritis.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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