September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
One-Year SDOCT Follow Up of Retinoschisis in Eyes with Choroidal New Vascularization Secondary to High Myopia
Author Affiliations & Notes
  • Fenghua Wang
    Opthalmology, Shanghai Jiaotong University affliated First Peoples Hospital , Shanghai, China
  • Tonghui Feng
    Opthalmology, Shanghai Jiaotong University affliated First Peoples Hospital , Shanghai, China
  • Yanping Zhou
    Opthalmology, Shanghai Jiaotong University affliated First Peoples Hospital , Shanghai, China
  • Xiaodong Sun
    Opthalmology, Shanghai Jiaotong University affliated First Peoples Hospital , Shanghai, China
  • Xun Xu
    Opthalmology, Shanghai Jiaotong University affliated First Peoples Hospital , Shanghai, China
  • Footnotes
    Commercial Relationships   Fenghua Wang, Carl Zeiss Meditec (C); Tonghui Feng, None; Yanping Zhou, None; Xiaodong Sun, None; Xun Xu, None
  • Footnotes
    Support  NSFC81470640
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 5349. doi:
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    • Get Citation

      Fenghua Wang, Tonghui Feng, Yanping Zhou, Xiaodong Sun, Xun Xu; One-Year SDOCT Follow Up of Retinoschisis in Eyes with Choroidal New Vascularization Secondary to High Myopia. Invest. Ophthalmol. Vis. Sci. 2016;57(12):5349.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Macular retinoschisis and choroidal neovascularization (CNV) are normal change in high myopia eyes. We performed a retrospective, observational clinical study in a one-year cohort designed to investigate longitudinal change of macular schisis in pathological myopia patient with CNV using spectral domain OCT.

Methods :
There were 35 CNV secondary to high myopia included in this study. All eyes were performed SD OCT using high definition cross scans and 512*128 raster scans mode, refractive errors and axial length (AL) at baseline, following by OCT monthly for 12 months. The OCT images were evaluated by two independent graders for macular schisis, the height of schisis and retinal thickness.

Results : All patients received at least one injection of Anti-VEGF agent (median 3) . Mean vision acuity was improved from 48 to 69 ETDRS characters. Ten eyes were found combined retinoschisis. Fovea were involved in six eyes. Outer layer retinoschisis was observed in 9 eyes at baseline and the number did not change at Month 12. The inner layer schisis was observed in 3 eyes at baseline and 4 at Month 12. Mean height of schisis was 189±67microns at baseline and 196±102 microns at Month 12. There is no significant difference between the heights at different time point.

Conclusions : Retinoschisis in macular in PM CNV patients were not rare. One-year follow-up did not suggest significant progression of retinoschisis in the these eyes received intravitreal injection.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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