September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Therapeutic response of patients with Diabetic macular edema (DME) with micropulsed yellow laser 577nm and intravitreal bevacizumab
Author Affiliations & Notes
  • Geovanni jassiel Rios
    RETINA, HOSPITAL DE LA LUZ , MEXICO, DF, Mexico
  • SERGIO ROJAS
    RETINA, HOSPITAL DE LA LUZ , MEXICO, DF, Mexico
  • Footnotes
    Commercial Relationships   Geovanni Rios, None; SERGIO ROJAS, None
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 5358. doi:
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      Geovanni jassiel Rios, SERGIO ROJAS; Therapeutic response of patients with Diabetic macular edema (DME) with micropulsed yellow laser 577nm and intravitreal bevacizumab. Invest. Ophthalmol. Vis. Sci. 2016;57(12):5358.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : The aim of the study is to evaluate the therapeutic response of diabetic macular edema combining intravitreal bevacizumab + macular micropulsed yellow 577 nm laser treatment.

Methods : Patients from the Retina Department at "Hospital Nuestra Señora de la Luz" Mexico City diagnosed with diabetic macular edema were treated with intravitreal bevacizumab (monthly) + a single macular grid laser session with micropulsed yellow 577nm on the platform Iridex IQ 577. The parameters used: Spot: 100 microns / Lens: Volk Superquad / Power: 500 mW / Time: 200 ms / Duty cycle: 5%. At Month and 3 months of follow-up treatment we measured best corrected visual acuity (BCVA), central macular thickness (CMT) and macular volume (MV) with spectral domain Optical Coherence Tomography. Statistical Student t test was used to assess response to treatment.

Results : Combined therapy after 1 month follow-up, achieved an improvement in BCVA of 0.12 logMAR , with a reduction of 407 microns to 366 microns in central macular thickness (CMT), a reduction on macular volume of 10.32 to 9.82 mm3 being an average of 0.5 mm3 after the first month of treatment, being similar at 3 months of follow up and statistically significant. (p< 0.05)

Conclusions : Combined therapy in patients with diabetic macular edema is effective, being an alternative treatment therapy, antiangiogenic + macular yellow micropulsed laser.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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