September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
OCT Angiography of the Optic Nerve and Macula Blood Flow Following Clear Cornea Cataract Surgery
Author Affiliations & Notes
  • Spencer Langevin
    Ophthalmology, Nassau University Medical Center, East Meadow, New York, United States
  • Jared Smedley
    Ophthalmology, Nassau University Medical Center, East Meadow, New York, United States
  • Matheiu Bakhoum
    Ophthalmology, Nassau University Medical Center, East Meadow, New York, United States
  • Flavia Tzani
    Laservision.gr Clinical & Research Eye Institute, Athens, Greece
  • Henry Perry
    Ophthalmic Consultants of Long Island, Garden City, New York, United States
    Ophthalmology, Nassau University Medical Center, East Meadow, New York, United States
  • George Asimellis
    Laservision.gr Clinical & Research Eye Institute, Athens, Greece
  • A. John Kanellopoulos
    Laservision.gr Clinical & Research Eye Institute, Athens, Greece
    Ophthalmology, New York University, New York, New York, United States
  • Footnotes
    Commercial Relationships   Spencer Langevin, None; Jared Smedley, None; Matheiu Bakhoum, None; Flavia Tzani, None; Henry Perry, Alcon (C), Allergan (C), Blephex (C), Omidria (C); George Asimellis, None; A. Kanellopoulos, Alcon/WaveLight (C), Allergan (C), Avedro (C), i-Optics (C), ISP Surgical (C), Keramed (C)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 5464. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to Subscribers Only
      Sign In or Create an Account ×
    • Get Citation

      Spencer Langevin, Jared Smedley, Matheiu Bakhoum, Flavia Tzani, Henry Perry, George Asimellis, A. John Kanellopoulos; OCT Angiography of the Optic Nerve and Macula Blood Flow Following Clear Cornea Cataract Surgery. Invest. Ophthalmol. Vis. Sci. 2016;57(12):5464.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : Imaging of the retinal vasculature is an integral part of the evaluation of a large number of ocular diseases that may cause vision loss. Fluorescein angiography has been the modality of choice historically for evaluating retinal vasculature, however, there are risks of adverse effects and known defects in imaging all the layers of the retinal vasculature. Optical coherence tomography (OCT) angiography is a novel modality that can image vessels based on flow characteristics and may provide improved information. The purpose of this study was to evaluate the effect of small-incision clear-cornea cataract surgery on optic nerve and macula blood flow studied with OCT angiography, and to potentially screen for subclinical Irvine-Gass syndrome.

Methods : We evaluated 35 consecutive clear-cornea cataract surgery cases (17 phacoemulsification, 18 femtosecond laser-assisted (LenSx, Alcon, Ft. Worth, TX) capsulotomy and lens fragmentation. We evaluated visual acuity, refraction, keratometry, tomography, pachymetry, endothelial cell counts, and intraocular pressure. AngioVue Imaging System (Optovue, Fremont, CA) images of the optic nerve and macula were obtained preoperatively, at day-1, week-1 and week-4, constructing angiography of the retinal and choroidal microvasculature, with the ability to isolate vasculature and circulation in individual layers of customized height in the retina and choroid.

Results : In 21/35 cases preoperative and postoperative images were of adequate quality to be analyzed and compared, largely due to cataract-related media opacity. Optic nerve angioflow showed transient blood flow increase (both at radial peripapillary level and on the optic disc) at day-1 in 5 cases (2 manual, 3 femto), not observed thereafter. There was no macula angioflow deviation detectable from baseline at any follow-up interval within all four levels studied: superficial capillary, deep capillary, outer retina, or choriocapillary layers. There was no statistical difference in the findings between the manual vs femto-assisted subgroups.

Conclusions : We present a novel, non-invasive objective technique in evaluating potential optic nerve and or macula microvascular changes. Transient vascular flow pathology was evident in uneventful clear cornea cataract surgery. This data may aid clinicians in the post-operative anti-inflammatory regimen choices and length of therapy.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×