September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Optical coherence tomography angiography features in retinal artery occlusion
Author Affiliations & Notes
  • Nikoly Tigani Fares
    Federal University of Sao Paulo, Sao Paulo, SP, Brazil
  • Joao Rafael de Oliveira Dias
    Federal University of Sao Paulo, Sao Paulo, SP, Brazil
  • Marina Pereira Neder
    Federal University of Sao Paulo, Sao Paulo, SP, Brazil
  • Claudio Zett Lobos
    Federal University of Sao Paulo, Sao Paulo, SP, Brazil
  • Eduardo Amorim Novais
    Federal University of Sao Paulo, Sao Paulo, SP, Brazil
  • Belfort Rubens
    Federal University of Sao Paulo, Sao Paulo, SP, Brazil
  • Footnotes
    Commercial Relationships   Nikoly Fares, None; Joao Dias, None; Marina Neder, None; Claudio Lobos, None; Eduardo Novais, None; Belfort Rubens, None
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 5477. doi:
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      Nikoly Tigani Fares, Joao Rafael de Oliveira Dias, Marina Pereira Neder, Claudio Zett Lobos, Eduardo Amorim Novais, Belfort Rubens; Optical coherence tomography angiography features in retinal artery occlusion. Invest. Ophthalmol. Vis. Sci. 2016;57(12):5477.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To describe the retinal microvasculature of the eyes with nonarteritic retinal artery occlusion (RAO) based on optical coherence tomography angiography (OCT-A).

Methods : Cross-sectional, prospective, observational study. Patients with artery occlusion – central, branch or cillioretinal – were prospectively recruited to be imaged on spectral-domain OCT-A (RTVue XR Avanti; Optovue, Inc, Fremont, California, USA), FA (Spectralis HRA Heidelberg Engineering, Heidelberg, Germany) and color fundus phtograph on the same day. Qualitative analysis of the morphology of the superficial and deep retinal capillary plexuses, and radial peripapillary capillaries was performed. Retinal vasculature images using optical coherence tomography angiography were correlated with fluorescein angiography images. All patients were referred to a clinical evaluation for the investigation of systemic diseases.

Results : Ten patients with retinal artery occlusion were included in this study. OCT-A findings were similar to FA finding for the demonstration of retinal ischemia and neovascularization. Distinct differences in the distribution of zones of decreased vascular perfusion between the superficial and deep retinal capillary plexus corresponding to areas of delayed dye perfusion on fluorescein angiography were demonstrated using OCT angiogram. However, OCT-A was not able to evaluate peripheral retina due to restrict scanning field.

Conclusions : OCT-A imaging can accurately discern retinal capillary plexuses at different levels in the eyes with retinal artery occlusion and may be sensitive for more precisely characterizing the extent of macular ischemia and monitoring vascular flow changes during the course of the disease. However, because this exam is restricted to the posterior pole, AF still remains the gold standard exam for peripheral retina imaging.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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