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Roberta Farci, Pietro Emanuele Napoli, Maurizio Fossarello; En-face optical coherence tomography angiography in central serous corioretinopathy. Invest. Ophthalmol. Vis. Sci. 2016;57(12):5479.
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© ARVO (1962-2015); The Authors (2016-present)
To analyze retinal layers and vascular plexus changes using optical coherence tomography angiography (OCT-A) in patients with acute and chronic central serous corioretinopathy (CSC).
Twenty-eyes of 20 patients with central serous corioretinopathy (ascertained by spectral domain optical coherence tomography OCT), fluorescein angiography (FA), and indocyanine green angiography (ICGA), were enrolled for en-face angio OCT examination, and studied in comparison to 20 controls using a spectral-domain OCT device (AngioVue RTVue XR Avanti, Optovue).
In patients with CSC, OCT angiography revealed the depletion of main vessels in the superficial capillary plexus and in the avascular foveal zones borders and the reduction of vascular flow in the superficial and the deep vascular network, as quantified by the software OCT (thickness ILM-EPR flow density and grid based flow density). Moreover, en-face OCT imaging permitted to describe three different chorocapillaris morphological patterns: a) marbled pattern, b) rough grain pattern and, c) fine grain pattern.
En face OCT-A imaging is an easy, reproducible, non-invasive and effective tool to visualise retinal and choroidal changes in patients affected by CSC. It provides complementary morphological and blood flow quantitative information, and reveals peculiar imaging patterns at the level of choriocapillaris/choroid layer which deserve further studies.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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