September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Vision-related quality of life and visual function, as measured by three differrent visual field tests
Author Affiliations & Notes
  • Dana Blumberg
    Ophthalmology, Columbia University Medical Center, New York, New York, United States
  • alisa prager
    Ophthalmology, Columbia University Medical Center, New York, New York, United States
  • Lama Al-Aswad
    Ophthalmology, Columbia University Medical Center, New York, New York, United States
  • Donald Charles Hood
    Psychology and Ophthalmic Science, Columbia University, NY, New York, United States
  • Jeffrey M Liebmann
    Ophthalmology, Columbia University Medical Center, New York, New York, United States
  • Qi Yu
    Ophthalmology, Columbia University Medical Center, New York, New York, United States
  • George A Cioffi
    Ophthalmology, Columbia University Medical Center, New York, New York, United States
  • C Gustavo De Moraes
    Ophthalmology, Columbia University Medical Center, New York, New York, United States
  • Footnotes
    Commercial Relationships   Dana Blumberg, None; alisa prager, None; Lama Al-Aswad, None; Donald Hood, Heidelbergberg, Englineering (F), Topcon (F), Topcon (C); Jeffrey Liebmann, Carl Zeiss, Meditech (C); Qi Yu, None; George Cioffi, None; C Gustavo De Moraes, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 5602. doi:
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    • Get Citation

      Dana Blumberg, alisa prager, Lama Al-Aswad, Donald Charles Hood, Jeffrey M Liebmann, Qi Yu, George A Cioffi, C Gustavo De Moraes; Vision-related quality of life and visual function, as measured by three differrent visual field tests. Invest. Ophthalmol. Vis. Sci. 2016;57(12):5602.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To examine the relationship between vision-related quality of life and visual function, as measured by a 24-2, 10-2, and modified visual field test the combined all points from the 10-2 and 24-2.

Methods : 78 eyes of 39 glaucoma patients within the entire range of 24-2 visual field damage completed the National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25). Three sets of integrated, binocular visual fields were calculated from the monocular fields of each patient. The first set contained 24-2 fields, the second 10-2 fields, and the third a modified visual field test that combined all points from the central 10-2 and 24-2. Univariable linear regression analyses were conducted to determine the contribution of each of the binocular fields in determining the variation in each domain of Rasch-calibrated NEI VFQ-25 scores seen among glaucoma patients.

Results : In univariable linear regression analysis, the coefficient of determination for Rasch-calibrated composite NEI VFQ-25 scores was r2 = 0.23 for the 24-2, r2 = 0.29 for the 10-2, and r2 = 0.32 for the combined 10-2 & 24-2. The combined 10-2 & 24-2 also performed better then 24-2 and 10-2 when looking at all individual NEI VFQ domain (p<0.001). Multivariable models including socioeconomic status, education, age, and number of glaucoma meds explained approximately 40% of the variance of the composite NEI VFQ score.

Conclusions : Visual function data from combined 10-2 and 24-2 visual field should be considered in determining vision-related quality of life in glaucoma pateints. This may be obtained by performing a separate 10-2 and 24-2 visual field and evaluating information from both, or, alternatively, modifying the current 24-2 test pattern to include additional central visual stimuli test points.[i] This approach could lead to new metrics of patient-important outcomes to be used in future clinical trials in glaucoma.


[i] Hood DC, Nguyen M, Ehrlich AC, et al. A test of a model of glaucomatous damage of the macula with high-density perimetry: implications for the locations of visual field test points. Transl Vis Sci Technol. 2014;3:5.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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