September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Selective laser trabeculoplasty reduces intraocular pressure fluctuation in response to the provocative water drinking test in open-angle glaucoma
Author Affiliations & Notes
  • Nathan Mitchell Kerr
    Glaucoma Investigation and Research Unit, Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia
  • Henry Lew
    Glaucoma Care, Melbourne, Victoria, Australia
  • Simon Skalicky
    Glaucoma Investigation and Research Unit, Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia
    Glaucoma Care, Melbourne, Victoria, Australia
  • Footnotes
    Commercial Relationships   Nathan Kerr, None; Henry Lew, None; Simon Skalicky, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 5614. doi:
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    • Get Citation

      Nathan Mitchell Kerr, Henry Lew, Simon Skalicky; Selective laser trabeculoplasty reduces intraocular pressure fluctuation in response to the provocative water drinking test in open-angle glaucoma. Invest. Ophthalmol. Vis. Sci. 2016;57(12):5614.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To determine the effect of selective laser trabeculoplasty on intraocular pressure fluctuations induced by the provocative water drinking test in patients with open-angle glaucoma.

Methods : Retrospective observational study. Patients with open angle glaucoma underwent the water drinking test before and at least 6 weeks after selective laser trabeculoplasty. One eye from each patient was selected at random. Intraocular pressure was measured with a Goldmann applanation tonometer at baseline and every 15 minutes for 45 minutes following a fluid challenge of 800 mL over 10 minutes. Peak intraocular pressure and maximum fluctuation from baseline were compared using repeated measures ANOVA and paired t-tests.

Results : Twenty eyes from 20 patients were included in this study. The mean patient age was 73.6 years ± 8.5 years and 70% of patients were female. Following selective laser trabeculoplasty there was a statistically significant reduction in maximum intraocular pressure from 22.1 ± 3.9 mmHg to 16.6 ± 3.0 mmHg (P < 0.00001) and fluctuation from baseline from 5.0 ± 2.5 mmHg to 2.5 ± 1.9 mmHg (P = 0.000677) in response to the water drinking test.

Conclusions : Patients with open angle glaucoma treated with selective laser trabeculoplasty have lower peak IOPs and less fluctuation in IOP in response to the provocative water drinking test.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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