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Ji C He; Relationship between Peripheral Retinal Shape and Central Refractive Error in the Emmetropic and Myopic Eyes. Invest. Ophthalmol. Vis. Sci. 2016;57(12):5748.
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© ARVO (1962-2015); The Authors (2016-present)
Axial elongation is a developmental process responsible for increasing the curvature of retinal shape in the human eye. The purpose of this study was to examine the relationship between peripheral retinal shape and central refractive error for young emmetropes and myopes.
Peripheral refraction across ±25 deg retinal eccentricities on the horizontal meridian was measured in the right eyes of 15 emmetropes (mean SE = -0.15±0.29D) and 19 myopes (mean SE = -2.50±1.39D), aged 18-30 years old, by using an open field autorefractor (WAM-5500). Peripheral eye length at the same gazes was also measured by using the Zeiss IOL Master. Relative peripheral eye length was then calculated for estimating retinal shape, and it was statistically correlated to central refractive error.
For all subjects, mean peripheral eye length was shorter than the central axial length (24.00±1.00mm) with a difference of -0.37±0.29mm nasally and -0.53±0.24mm temporally at 25 deg, and the temporal eye length was significantly different from the nasal side (t=2.61, p<0.01). When myopic group was separated from the emmetropic group, relative peripheral eye length was significantly shorter in myopes than in emmetropes (t=4.06, p<0.01) at 25 deg. As the relationship of the relative peripheral eye length with central refractive error was tested, the relative peripheral eye length was significantly correlated to central spherical equivalent only at the temporal side. For example, the correlation coefficients at the 20 deg temporal field were 0.61 (p<0.025) and 0.46 (p<0.05) for the emmetropes and myopes respectively, but no such significant correlation was found at the nasal side for either group. In either the emmetropic or the myopic group, the relative peripheral eye length changed from one subject to another even though they have central refractive errors very close to each other.
Peripheral retinal curvature is weakly linked to central refractive error for both emmetropic and low to intermediate myopic eyes at the temporal retinal side, but not at the nasal side. The relationship of the peripheral retinal shape with the refractive error varies substantially from individual to individual. The results suggest that the eyeball shape is not necessarily elongated axially along visual axis during myopia development and progression.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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